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LIG4

Description	DNA ligase 4

Gene and Protein Information

Gene ID	3981
Uniprot Accession IDs	P49917 Q8IY66 Q8TEU5
Ensembl ID	ENSG00000174405
Symbol	LIG4S
Chromosome	13
Family	Belongs to the ATP-dependent DNA ligase family.
Sequence	MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHGDAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISITLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILCGTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLEQLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFEDVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDVVKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSGIKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAIKALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDKCELQEENQYLI Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	452653	LIG4	DNA ligase 4	9598	VGNC:10471	OMA, EggNOG
Macaque	695475	LIG4	DNA ligase 4	9544		Inparanoid, OMA
Mouse	319583	Lig4	ligase IV, DNA, ATP-dependent	10090	MGI:1335098	Inparanoid, OMA, EggNOG
Rat	290907	Lig4	DNA ligase 4	10116	RGD:1304639	Inparanoid, OMA, EggNOG
Dog	485544	LIG4	DNA ligase 4	9615	VGNC:42675	Inparanoid, OMA, EggNOG
Horse	100051479	LIG4	DNA ligase 4	9796	VGNC:19665	Inparanoid, OMA, EggNOG
Cow	781252	LIG4	DNA ligase 4	9913	VGNC:30884	Inparanoid, OMA, EggNOG
Pig	100155891	LIG4	DNA ligase 4	9823		OMA, EggNOG
Opossum	100018117	LIG4	DNA ligase 4	13616		Inparanoid, OMA, EggNOG
Chicken	418764	LIG4	DNA ligase 4	9031	CGNC:12647	Inparanoid, OMA, EggNOG
Anole lizard	100561936	lig4	DNA ligase 4	28377		Inparanoid, OMA, EggNOG
Xenopus	549735	lig4	ligase IV, DNA, ATP-dependent	8364	XB-GENE-964443	Inparanoid, OMA, EggNOG
Zebrafish	569525	lig4	ligase IV, DNA, ATP-dependent	7955	ZDB-GENE-070820-10	Inparanoid, OMA, EggNOG
S.cerevisiae	854166	DNL4	DNA ligase (ATP) DNL4	4932	S000005531	Inparanoid, OMA, EggNOG

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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