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| Description | Glutamate receptor ionotropic, NMDA 2B |
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Gene and Protein Information
| Gene ID | 2904 |
|---|---|
| Uniprot Accession IDs | Q13224 Q12919 Q13220 Q13225 Q14CU4 Q9UM56 GluN2B |
| Ensembl ID | ENSG00000273079 |
| Symbol | NMDAR2B NR3 MRD6 NR2B hNR3 EIEE27 GluN2B NMDAR2B |
| Chromosome | 12 |
| Family | Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily. |
| Sequence |
MKPRAECCSPKFWLVLAVLAVSGSRARSQKSPPSIGIAVILVGTSDEVAIKDAHEKDDFHHLSVVPRVELVAMNETDPKSIITRICDLMSDRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQLKKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDTVPAEFPTGLISVSYDEWDYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTHEKRIYQSNMLNRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNKERKWERVGKWKDKSLQMKYYVWPRMCPETEEQEDDHLSIVTLEEAPFVIVESVDPLSGTCMRNTVPCQKRIVTENKTDEEPGYIKKCCKGFCIDILKKISKSVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVMKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPPFRFGTVPNGSTERNIRNNYAEMHAYMGKFNQRGVDDALLSLKTGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFASTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLGAAMALSLITFICEHLFYWQFRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEERQSVMNSPTATMNNTHSNILRLLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSYNNPPCEENLFSDYISEVERTFGNLQLKDSNVYQDHYHHHHRPHSIGSASSIDGLYDCDNPPFTTQSRSISKKPLDIGLPSSKHSQLSDLYGKFSFKSDRYSGHDDLIRSDVSDISTHTVTYGNIEGNAAKRRKQQYKDSLKKRPASAKSRREFDEIELAYRRRPPRSPDHKRYFRDKEGLRDFYLDQFRTKENSPHWEHVDLTDIYKERSDDFKRDSVSGGGPCTNRSHIKHGTGDKHGVVSGVPAPWEKNLTNVEWEDRSGGNFCRSCPSKLHNYSTTVTGQNSGRQACIRCEACKKAGNLYDISEDNSLQELDQPAAPVAVTSNASTTKYPQSPTNSKAQKKNRNKLRRQHSYDTFVDLQKEEAALAPRSVSLKDKGRFMDGSPYAHMFEMSAGESTFANNKSSVPTAGHHHHNNPGGGYMLSKSLYPDRVTQNPFIPTFGDDQCLLHGSKSYFFRQPTVAGASKARPDFRALVTNKPVVSALHGAVPARFQKDICIGNQSNPCVPNNKNPRAFNGSSNGHVYEKLSSIESDV
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Macaque | 698571 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 9544 | Inparanoid, OMA | |
| Mouse | 14812 | Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 10090 | MGI:95821 | Inparanoid, OMA |
| Rat | 24410 | Grin2b | glutamate ionotropic receptor NMDA type subunit 2B | 10116 | RGD:2738 | Inparanoid, OMA |
| Dog | 494009 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 9615 | VGNC:41493 | Inparanoid, OMA |
| Horse | 100063746 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 9796 | VGNC:18589 | Inparanoid, OMA |
| Cow | 537804 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 9913 | VGNC:29647 | Inparanoid, OMA |
| Pig | 100626022 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 9823 | Inparanoid, OMA | |
| Opossum | 100017355 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 13616 | Inparanoid, OMA | |
| Chicken | 417965 | GRIN2B | glutamate ionotropic receptor NMDA type subunit 2B | 9031 | CGNC:8954 | Inparanoid, OMA |
| Zebrafish | 559976 | grin2bb | glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b | 7955 | ZDB-GENE-061207-27 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Ion channel / Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors / NR2B/GRIN2B subfamily / Glutamate receptor ionotropic, nmda 2b
protein / Ion channel / Glutamate-gated ion channel (GIC) Family of Neurotransmitter Receptors / NR2B/GRIN2B subfamily / Glutamate receptor ionotropic, nmda 2b
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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