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FBL

Description rRNA 2'-O-methyltransferase fibrillarin

Gene and Protein Information

Gene ID 2091
Uniprot Accession IDs P22087 B5BUE8 O75259 Q6IAT5 Q9UPI6
Ensembl ID ENSG00000105202
Symbol FIB1 FLRN FIB FLRN Nop1 RNU3IP1
Chromosome 19
Family Belongs to the methyltransferase superfamily. Fibrillarin family.
Sequence
MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 456031 FBL fibrillarin 9598 VGNC:11012 OMA, EggNOG
Mouse 14113 Fbl fibrillarin 10090 MGI:95486 OMA, EggNOG
Rat 292747 Fbl fibrillarin 10116 RGD:1305542 OMA, EggNOG
Dog 476460 FBL fibrillarin 9615 VGNC:40748 OMA, EggNOG
Horse 100064571 FBL fibrillarin 9796 VGNC:17928 OMA, EggNOG
Cow 538548 FBL fibrillarin 9913 VGNC:28879 OMA, EggNOG
Pig 100626002 FBL fibrillarin 9823 OMA, EggNOG
Opossum 100014751 FBL fibrillarin 13616 OMA, EggNOG
Xenopus 394705 fbl fibrillarin 8364 XB-GENE-970225 OMA, EggNOG
Zebrafish 406275 fbl fibrillarin 7955 ZDB-GENE-040426-1936 OMA, EggNOG
C. elegans 179999 fib-1 rRNA 2'-O-methyltransferase fibrillarin 6239 OMA, EggNOG
S.cerevisiae 851548 NOP1 rRNA methyltransferase NOP1 4932 S000002172 OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    ribonucleoprotein    /    rRNA 2'-O-methyltransferase fibrillarin
protein    /    nucleic acid binding    /    methyltransferase    /    rRNA 2'-O-methyltransferase fibrillarin
DTO Classes
protein    /    Enzyme    /    Transferase    /    Methyltransferase    /    rRNA 2'-O-methyltransferase fibrillarin

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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