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NPR1

Description Atrial natriuretic peptide receptor 1

Gene and Protein Information

Gene ID 4881
Uniprot Accession IDs P16066 B0ZBF0 Q5SR08 Q6P4Q3
Ensembl ID ENSG00000169418
Symbol ANPRA ANPa NPRA ANPRA GUC2A GUCY2A
Chromosome 1
Family Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Sequence
MPGPRRPAGSRLRLLLLLLLPPLLLLLRGSHAGNLTVAVVLPLANTSYPWSWARVGPAVELALAQVKARPDLLPGWTVRTVLGSSENALGVCSDTAAPLAAVDLKWEHNPAVFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVKDEYALTTRAGPSYAKLGDFVAALHRRLGWERQALMLYAYRPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDDLSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGEDYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDVSARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDGLVNTIPASFHDGLLLYIQAVTETLAHGGTVTDGENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPENGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEPSSLERHLRSAGSRLTLSGRGSNYGSLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIELTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFRDLDPEQGHTVYAKKLWTAPELLRMASPPVRGSQAGDVYSFGIILQEIALRSGVFHVEGLDLSPKEIIERVTRGEQPPFRPSLALQSHLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSSNILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 457329 NPR1 natriuretic peptide receptor 1 9598 VGNC:1419 OMA, EggNOG
Macaque 715598 NPR1 natriuretic peptide receptor 1 9544 Inparanoid, OMA, EggNOG
Mouse 18160 Npr1 natriuretic peptide receptor 1 10090 MGI:97371 Inparanoid, OMA, EggNOG
Rat 24603 Npr1 natriuretic peptide receptor 1 10116 RGD:3195 Inparanoid, OMA, EggNOG
Dog 490455 NPR1 natriuretic peptide receptor 1 9615 VGNC:43928 Inparanoid, OMA, EggNOG
Cow 533048 NPR1 natriuretic peptide receptor 1 9913 VGNC:32213 Inparanoid, OMA, EggNOG
Pig 100153508 NPR1 natriuretic peptide receptor 1 9823 Inparanoid, OMA, EggNOG
Zebrafish 560653 npr1a natriuretic peptide receptor 1a 7955 ZDB-GENE-060503-539 Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    lyase    /    adenylate cyclase    /    Atrial natriuretic peptide receptor 1
protein    /    lyase    /    guanylate cyclase    /    Atrial natriuretic peptide receptor 1
DTO Classes
protein    /    Kinase    /    Protein kinase    /    RGC group    /    RGC family    /    Atrial natriuretic peptide receptor 1

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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