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APEX1

Description	DNA-(apurinic or apyrimidinic site) lyase

Gene and Protein Information

Gene ID	328
Uniprot Accession IDs	P27695 Q969L5 Q99775
Ensembl ID	ENSG00000100823
Symbol	APE APE1 APEX APX HAP1 REF1 APE APX APE1 APEN APEX HAP1 REF1
Chromosome	14
Family	Belongs to the DNA repair enzymes AP/ExoA family.
Sequence	MPKRGKKGAVAEDGDELRTEPEAKKSKTAAKKNDKEAAGEGPALYEDPPDQKTSPSGKPATLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWSAPSDKEGYSGVGLLSRQCPLKVSYGIGDEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLVRLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGFGELLQAVPLADSFRHLYPNTPYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKIRSKALGSDHCPITLYLAL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	465200	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1	9598	VGNC:8393	Inparanoid, OMA, EggNOG
Mouse	11792	Apex1	apurinic/apyrimidinic endonuclease 1	10090	MGI:88042	Inparanoid, OMA, EggNOG
Rat	79116	Apex1	apurinic/apyrimidinic endodeoxyribonuclease 1	10116	RGD:2126	Inparanoid, OMA, EggNOG
Dog	482558	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1	9615	VGNC:54195	Inparanoid, OMA, EggNOG
Horse	100072588	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1	9796	VGNC:15404	Inparanoid, OMA, EggNOG
Cow	281630	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1	9913	VGNC:26011	Inparanoid, OMA, EggNOG
Opossum	100029539	APEX1	apurinic/apyrimidinic endodeoxyribonuclease 1	13616		Inparanoid, EggNOG
Anole lizard	100554177	apex1	apurinic/apyrimidinic endodeoxyribonuclease 1	28377		Inparanoid, OMA, EggNOG
Xenopus	394929	apex1	APEX nuclease (multifunctional DNA repair enzyme) 1	8364	XB-GENE-977072	Inparanoid, OMA, EggNOG
Zebrafish	406730	apex1	APEX nuclease (multifunctional DNA repair enzyme) 1	7955	ZDB-GENE-040426-2761	Inparanoid, OMA, EggNOG
C. elegans	173069	exo-3	DNA-(apurinic or apyrimidinic site) lyase	6239		Inparanoid, OMA, EggNOG

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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