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Targets(Human)
CHRNA1

CHRNA1

Description	Acetylcholine receptor subunit alpha

Gene and Protein Information

Gene ID	1134
Uniprot Accession IDs	P02708 B4DRV6 D3DPE8
Ensembl ID	ENSG00000138435
Symbol	ACHRA CHNRA ACHRA ACHRD CHRNA CMS1A CMS1B CMS2A FCCMS SCCMS
Chromosome	2
Family	Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.
Sequence	MEPWPLLLLFSLCSAGLVLGSEHETRLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQGDMVDLPRPSCVTLGVPLFSHLQNEQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNADGDFAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFFSTMKRPSREKQDKKIFTEDIDISDISGKPGPPPMGFHSPLIKHPEVKSAIEGIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCIIGTLAVFAGRLIELNQQG Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	470583	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9598	VGNC:136	OMA, EggNOG
Macaque	698578	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9544		Inparanoid, OMA, EggNOG
Mouse	11435	Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	10090	MGI:87885	Inparanoid, OMA, EggNOG
Rat	79557	Chrna1	cholinergic receptor nicotinic alpha 1 subunit	10116	RGD:69277	Inparanoid, OMA, EggNOG
Dog	403757	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9615	VGNC:39236	Inparanoid, OMA, EggNOG
Horse	100065034	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9796	VGNC:16522	Inparanoid, OMA, EggNOG
Cow	338070	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9913	VGNC:27322	Inparanoid, OMA, EggNOG
Opossum	100025856	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	13616		Inparanoid, OMA, EggNOG
Platypus	100084387	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9258		Inparanoid, OMA, EggNOG
Chicken	395608	CHRNA1	cholinergic receptor nicotinic alpha 1 subunit	9031	CGNC:7068	Inparanoid, OMA
Anole lizard	100557909	chrna1	cholinergic receptor nicotinic alpha 1 subunit	28377		Inparanoid, OMA, EggNOG
Xenopus	100145177	chrna1	cholinergic receptor, nicotinic alpha 1	8364	XB-GENE-977139	Inparanoid, OMA, EggNOG
Zebrafish	30725	chrna1	cholinergic receptor, nicotinic, alpha 1 (muscle)	7955	ZDB-GENE-980526-137	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    transporter    /    ligand-gated ion channel    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    ion channel    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    acetylcholine receptor    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    GABA receptor    /    Acetylcholine receptor subunit alpha
protein    /    transporter    /    receptor    /    Acetylcholine receptor subunit alpha

DTO Classes
protein / Ion channel / Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family / Acetylcholine receptor subfamily / Alpha-1/CHRNA1 sub-subfamily / Acetylcholine receptor subunit alpha

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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