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Targets(Human)
ACVR1

ACVR1

Description	Activin receptor type-1

Gene and Protein Information

Gene ID	90
Uniprot Accession IDs	Q04771
Ensembl ID	ENSG00000115170
Symbol	ACVRLK2 FOP ALK2 SKR1 TSRI ACTRI ACVR1A ACVRLK2
Chromosome	2
Family	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence	MVDGVMILPVLIMIALPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSINDGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNFHLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTLADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSRDEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTLDTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVMHSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVSNGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQNPSARLTALRIKKTLTKIDNSLDKLKTDC Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	470565	ACVR1	activin A receptor type 1	9598	VGNC:56	OMA, EggNOG
Macaque	697935	ACVR1	activin A receptor type 1	9544		Inparanoid, OMA, EggNOG
Mouse	11477	Acvr1	activin A receptor, type 1	10090	MGI:87911	Inparanoid, OMA, EggNOG
Rat	79558	Acvr1	activin A receptor type 1	10116	RGD:620200	Inparanoid, OMA, EggNOG
Dog	478757	ACVR1	activin A receptor type 1	9615	VGNC:37561	Inparanoid, OMA
Horse	100050899	ACVR1	activin A receptor type 1	9796	VGNC:15035	Inparanoid, OMA
Cow	338068	ACVR1	activin A receptor type 1	9913	VGNC:25592	Inparanoid, OMA
Pig	100152307	ACVR1	activin A receptor type 1	9823		Inparanoid, OMA
Opossum	100021438	ACVR1	activin A receptor type 1	13616		Inparanoid, OMA
Anole lizard	100552279	acvr1	activin A receptor type 1	28377		Inparanoid, OMA
Xenopus	550111	acvr1	activin A receptor type 1	8364	XB-GENE-478850	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-1
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-1
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-1
protein    /    receptor    /    protein kinase    /    Activin receptor type-1
protein    /    receptor    /    transferase    /    Activin receptor type-1
protein    /    receptor    /    kinase    /    Activin receptor type-1

DTO Classes
protein / Kinase / Protein kinase / TKL group / STKR family / STKR Type 1 subfamily / Activin receptor type-1

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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