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Targets(Human)
CHRNA7

CHRNA7

Description	Neuronal acetylcholine receptor subunit alpha-7

Gene and Protein Information

Gene ID	1139
Uniprot Accession IDs	P36544 A8K7Q4 B4DFS0 Q15826 Q8IUZ4 Q96RH2 Q99555 Q9BXH0
Ensembl ID	ENSG00000175344
Symbol	NACHRA7 NACHRA7 CHRNA7-2
Chromosome	15
Family	Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-7/CHRNA7 sub-subfamily.
Sequence	MRCSPGGVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	467639	CHRNA7	cholinergic receptor nicotinic alpha 7 subunit	9598		OMA, EggNOG
Macaque	574230	CHRNA7	cholinergic receptor nicotinic alpha 7 subunit	9544		Inparanoid, OMA, EggNOG
Mouse	11441	Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	10090	MGI:99779	Inparanoid, OMA, EggNOG
Rat	25302	Chrna7	cholinergic receptor nicotinic alpha 7 subunit	10116	RGD:2348	Inparanoid, OMA, EggNOG
Dog	488696	CHRNA7	cholinergic receptor nicotinic alpha 7 subunit	9615		Inparanoid, OMA, EggNOG
Horse	100060521	LOC100060521	neuronal acetylcholine receptor subunit alpha-7	9796		OMA, EggNOG
Pig	100415931	CHRNA7	cholinergic receptor nicotinic alpha 7 subunit	9823		OMA, EggNOG
Opossum	100027128	LOC100027128	neuronal acetylcholine receptor subunit alpha-7	13616		Inparanoid, EggNOG
Chicken	374001	CHRNA7	cholinergic receptor nicotinic alpha 7 subunit	9031	CGNC:48996	Inparanoid, OMA, EggNOG
Zebrafish	394199	chrna7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	7955	ZDB-GENE-040108-3	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    transporter    /    ligand-gated ion channel    /    Neuronal acetylcholine receptor subunit alpha-7
protein    /    transporter    /    ion channel    /    Neuronal acetylcholine receptor subunit alpha-7
protein    /    transporter    /    acetylcholine receptor    /    Neuronal acetylcholine receptor subunit alpha-7
protein    /    transporter    /    GABA receptor    /    Neuronal acetylcholine receptor subunit alpha-7
protein    /    transporter    /    receptor    /    Neuronal acetylcholine receptor subunit alpha-7

DTO Classes
protein / Ion channel / Neurotransmitter receptor, Cys loop, ligand-gated ion channel (LIC) family / Acetylcholine receptor subfamily / Alpha-7/CHRNA7 sub-subfamily / Neuronal acetylcholine receptor subunit alpha-7

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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