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| Description | Vascular endothelial growth factor receptor 1 |
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Gene and Protein Information
| Gene ID | 2321 |
|---|---|
| Uniprot Accession IDs | P17948 A3E342 A3E344 A8KA71 B0LPF1 B2BF46 B2BF47 B2BF48 B3FR89 B5A923 F5H5L6 O60722 P16057 Q12954 VEGFR-1 |
| Ensembl ID | ENSG00000102755 |
| Symbol | FLT FRT VEGFR1 FLT FLT-1 VEGFR1 VEGFR-1 |
| Chromosome | 13 |
| Family | Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. |
| Sequence |
MVSYWDTGVLLCALLSCLLLTGSSSGSKLKDPELSLKGTQHIMQAGQTLHLQCRGEAAHKWSLPEMVSKESERLSITKSACGRNGKQFCSTLTLNTAQANHTGFYSCKYLAVPTSKKKETESAIYIFISDTGRPFVEMYSEIPEIIHMTEGRELVIPCRVTSPNITVTLKKFPLDTLIPDGKRIIWDSRKGFIISNATYKEIGLLTCEATVNGHLYKTNYLTHRQTNTIIDVQISTPRPVKLLRGHTLVLNCTATTPLNTRVQMTWSYPDEKNKRASVRRRIDQSNSHANIFYSVLTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEKSARYLTRGYSLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAVSSFPDPALYPLGSRQILTCTAYGIPQPTIKWFWHPCNHNHSEARCDFCSNNEESFILDADSNMGNRIESITQRMAIIEGKNKMASTLVVADSRISGIYICIASNKVGTVGRNISFYITDVPNGFHVNLEKMPTEGEDLKLSCTVNKFLYRDVTWILLRTVNNRTMHYSISKQKMAITKEHSITLNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNLSDHTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQEPGIILGPGSSTLFIERVTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFIRKMKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSVTSSESFASSGFQEDKSLSDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLGDLLQANVQQDGKDYIPINAILTGNSGFTYSTPAFSEDFFKESISAPKFNSGSSDDVRYVNAFKFMSLERIKTFEELLPNATSMFDDYQGDSSTLLASPMLKRFTWTDSKPKASLKIDLRVTSKSKESGLSDVSRPSFCHSSCGHVSEGKRRFTYDHAELERKIACCSPPPDYNSVVLYSTPPI
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 452512 | FLT1 | fms related tyrosine kinase 1 | 9598 | VGNC:7287 | OMA, EggNOG |
| Macaque | 574133 | FLT1 | fms related tyrosine kinase 1 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 14254 | Flt1 | FMS-like tyrosine kinase 1 | 10090 | MGI:95558 | Inparanoid, OMA, EggNOG |
| Rat | 54251 | Flt1 | FMS-related tyrosine kinase 1 | 10116 | RGD:2621 | Inparanoid, OMA, EggNOG |
| Dog | 403727 | FLT1 | fms related tyrosine kinase 1 | 9615 | VGNC:40907 | Inparanoid, OMA, EggNOG |
| Horse | 100033957 | FLT1 | fms related tyrosine kinase 1 | 9796 | VGNC:18067 | Inparanoid, OMA, EggNOG |
| Cow | 503620 | FLT1 | fms related tyrosine kinase 1 | 9913 | VGNC:29041 | Inparanoid, OMA, EggNOG |
| Pig | 396763 | FLT1 | fms related tyrosine kinase 1 | 9823 | OMA, EggNOG | |
| Opossum | 100025304 | FLT1 | fms related tyrosine kinase 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | FLT1 | fms related tyrosine kinase 1 [Source:HGNC Symbol;Acc:HGNC:3763] | 9258 | OMA, EggNOG | ||
| Chicken | 374100 | FLT1 | fms related tyrosine kinase 1 | 9031 | CGNC:49041 | Inparanoid, OMA |
| Anole lizard | 100556703 | flt1 | fms related tyrosine kinase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Zebrafish | 544667 | flt1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 7955 | ZDB-GENE-050407-1 | Inparanoid, OMA, EggNOG |
| Fruitfly | 34127 | Pvr | PDGF- and VEGF-receptor related | 7227 | FBgn0032006 | Inparanoid, EggNOG |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TK group / VEGFR family / Vascular endothelial growth factor receptor 1
protein / Kinase / Protein kinase / TK group / VEGFR family / Vascular endothelial growth factor receptor 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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