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ZAP70

Description	Tyrosine-protein kinase ZAP-70

Gene and Protein Information

Gene ID	7535
Uniprot Accession IDs	P43403 A6NFP4 Q6PIA4 Q8IXD6 Q9UBS6
Ensembl ID	ENSG00000115085
Symbol	SRK SRK STD TZK STCD IMD48 ADMIO2 ZAP-70
Chromosome	2
Family	Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.
Sequence	MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRDAMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLKLKADGLIYCLKEACPNSSASNASGAAAPTLPAHPSTLTHPQRRIDTLNSDGYTPEPARITSPDKPRPMPMDTSVYESPYSDPEELKDKKLFLKRDNLLIADIELGCGNFGSVRQGVYRMRKKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPLHKFLVGKREEIPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMAFIEQGKRMECPPECPPELYALMSDCWIYKWEDRPDFLTVEQRMRACYYSLASKVEGPPGSTQKAEAACA Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	459427	ZAP70	zeta chain of T cell receptor associated protein kinase 70	9598	VGNC:2916	OMA, EggNOG
Macaque	707555	LOC707555	tyrosine-protein kinase ZAP-70	9544		OMA, EggNOG
Mouse	22637	Zap70	zeta-chain (TCR) associated protein kinase	10090	MGI:99613	Inparanoid, OMA, EggNOG
Rat	301348	Zap70	zeta chain of T cell receptor associated protein kinase 70	10116	RGD:3983	Inparanoid, EggNOG
Dog	100271860	ZAP70	zeta chain of T cell receptor associated protein kinase 70	9615	VGNC:54555	Inparanoid, OMA
Horse	100147296	ZAP70	zeta chain of T-cell receptor associated protein kinase 70	9796	VGNC:25124	Inparanoid, OMA
Cow	504509	ZAP70	zeta chain of T-cell receptor associated protein kinase 70	9913	VGNC:37050	Inparanoid, OMA
Pig	100739325	LOC100739325	tyrosine-protein kinase ZAP-70	9823		Inparanoid, OMA
Chicken	420086	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	9031	CGNC:1027	Inparanoid, OMA
Xenopus	448557	zap70	zeta chain of T cell receptor associated protein kinase 70	8364	XB-GENE-956409	Inparanoid, OMA
Zebrafish	553615	zap70	zeta chain of T cell receptor associated protein kinase 70	7955	ZDB-GENE-050522-257	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TK group / SYK family / Tyrosine-protein kinase zap-70

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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