ERCC4

Description	DNA repair endonuclease XPF

Gene and Protein Information

Gene ID	2072
Uniprot Accession IDs	Q92889 A5PKV6 A8K111 O00140 Q8TD83
Ensembl ID	ENSG00000175595
Symbol	ERCC11 XPF XPF RAD1 FANCQ XFEPS ERCC11
Chromosome	16
Family	Belongs to the XPF family.
Sequence	MESGQPARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPACLVLVLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAAFGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPGKPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVRGTASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTPEMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSNDISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDFIHTSFAEVVSKGKGKK Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	453935	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9598	VGNC:9004	OMA, EggNOG
Macaque	712641	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9544		Inparanoid, OMA, EggNOG
Mouse	50505	Ercc4	excision repair cross-complementing rodent repair deficiency, complementation group 4	10090	MGI:1354163	Inparanoid, OMA, EggNOG
Rat		AABR07029002.2	-	10116		OMA, EggNOG
Dog	479842	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9615	VGNC:40444	Inparanoid, OMA, EggNOG
Horse	100050812	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9796	VGNC:51128	Inparanoid, OMA, EggNOG
Cow	516371	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9913	VGNC:28571	Inparanoid, OMA, EggNOG
Pig	100516427	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9823		Inparanoid, OMA, EggNOG
Opossum	100024202	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	13616		Inparanoid, OMA, EggNOG
Chicken	416420	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit	9031	CGNC:2155	Inparanoid, OMA, EggNOG
Anole lizard	100567423	ercc4	ERCC excision repair 4, endonuclease catalytic subunit	28377		Inparanoid, OMA, EggNOG
Xenopus	100145552	ercc4	excision repair cross-complementation group 4	8364	XB-GENE-986815	Inparanoid, OMA, EggNOG
Zebrafish	327322	ercc4	excision repair cross-complementation group 4	7955	ZDB-GENE-030131-5533	Inparanoid, OMA, EggNOG
Fruitfly	31373	mei-9	meiotic 9	7227	FBgn0002707	Inparanoid, EggNOG
S.cerevisiae	856085	RAD1	ssDNA endodeoxyribonuclease RAD1	4932	S000005943	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    DNA binding protein    /    DNA repair endonuclease XPF
protein    /    nucleic acid binding    /    nuclease    /    DNA repair endonuclease XPF
protein    /    nucleic acid binding    /    endodeoxyribonuclease    /    DNA repair endonuclease XPF

DTO Classes
protein / Enzyme / Nuclease / Endodeoxyribonuclease / DNA repair endonuclease XPF

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography