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ACVR2A

Description Activin receptor type-2A

Gene and Protein Information

Gene ID 92
Uniprot Accession IDs P27037 B2RAB8 B4DWQ2 D3DP85 Q53TH4 Q6NWV2 Q92474
Ensembl ID ENSG00000121989
Symbol ACVR2 ACVR2 ACTRII
Chromosome 2
Family Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Sequence
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWEKDRTNQTGVEPCYGDKDKRRHCFATWKNISGSIEIVKQGCWLDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 459646 ACVR2A activin A receptor type 2A 9598 VGNC:10526 OMA, EggNOG
Macaque 707017 ACVR2A activin A receptor type 2A 9544 Inparanoid, OMA, EggNOG
Mouse 11480 Acvr2a activin receptor IIA 10090 MGI:102806 Inparanoid, OMA, EggNOG
Rat 29263 Acvr2a activin A receptor type 2A 10116 RGD:70911 Inparanoid, OMA, EggNOG
Dog 476140 ACVR2A activin A receptor type 2A 9615 VGNC:37564 Inparanoid, OMA
Horse 100049823 ACVR2A activin A receptor type 2A 9796 VGNC:15038 Inparanoid, OMA
Cow 281598 ACVR2A activin A receptor type 2A 9913 VGNC:25595 Inparanoid, OMA
Opossum 100018756 ACVR2A activin A receptor type 2A 13616 Inparanoid, OMA
Chicken 396324 ACVR2A activin A receptor type 2A 9031 CGNC:9451 Inparanoid, OMA
Anole lizard 100562173 acvr2a activin A receptor type 2A 28377 Inparanoid, OMA
Xenopus 100216172 acvr2a activin A receptor type 2A 8364 XB-GENE-484012 Inparanoid, OMA
Zebrafish 553359 acvr2aa activin A receptor type 2Aa 7955 ZDB-GENE-980526-227 Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    receptor    /    protein kinase receptor    /    Activin receptor type-2a
protein    /    receptor    /    TGF-beta receptor    /    Activin receptor type-2a
protein    /    receptor    /    serine/threonine protein kinase receptor    /    Activin receptor type-2a
protein    /    receptor    /    protein kinase    /    Activin receptor type-2a
protein    /    receptor    /    transferase    /    Activin receptor type-2a
protein    /    receptor    /    kinase    /    Activin receptor type-2a
DTO Classes
protein    /    Kinase    /    Protein kinase    /    TKL group    /    STKR family    /    STKR Type 2 subfamily    /    Activin receptor type-2a

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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