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BRAF

Description	Serine/threonine-protein kinase B-raf

Gene and Protein Information

Gene ID	673
Uniprot Accession IDs	P15056 A4D1T4 B6HY61 B6HY62 B6HY63 B6HY64 B6HY65 B6HY66 Q13878 Q3MIN6 Q9UDP8 Q9Y6T3
Ensembl ID	ENSG00000157764
Symbol	BRAF1 RAFB1 NS7 B-raf BRAF1 RAFB1 B-RAF1
Chromosome	7
Family	Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Sequence	MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	463781	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9598	VGNC:14003	OMA, EggNOG
Mouse	109880	Braf	Braf transforming gene	10090	MGI:88190	Inparanoid, OMA, EggNOG
Rat	114486	Braf	B-Raf proto-oncogene, serine/threonine kinase	10116	RGD:619908	Inparanoid, OMA, EggNOG
Dog	475526	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9615	VGNC:38514	Inparanoid, OMA, EggNOG
Horse	100065760	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9796	VGNC:15875	Inparanoid, OMA, EggNOG
Cow	536051	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9913	VGNC:26551	OMA, EggNOG
Pig	100514612	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9823		OMA, EggNOG
Opossum	100024057	BRAF	B-Raf proto-oncogene, serine/threonine kinase	13616		Inparanoid, OMA, EggNOG
Chicken	396239	BRAF	B-Raf proto-oncogene, serine/threonine kinase	9031	CGNC:9744	Inparanoid, OMA
Anole lizard	100556317	braf	B-Raf proto-oncogene, serine/threonine kinase	28377		Inparanoid, OMA
Xenopus	779570	braf	B-Raf proto-oncogene, serine/threonine kinase	8364	XB-GENE-1014202	Inparanoid, OMA
Zebrafish	403065	braf	B-Raf proto-oncogene, serine/threonine kinase	7955	ZDB-GENE-040805-1	Inparanoid, OMA

DTO Classes
protein / Kinase / Protein kinase / TKL group / RAF family / Serine/threonine-protein kinase b-raf

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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