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Targets(Human)
CAPN1

CAPN1

Description	Calpain-1 catalytic subunit

Gene and Protein Information

Gene ID	823
Uniprot Accession IDs	P07384 Q2TTR0 Q6DHV4
Ensembl ID	ENSG00000014216
Symbol	CANPL1 CANP muCL CANP1 SPG76 CANPL1 muCANP
Chromosome	11
Family	Belongs to the peptidase C2 family.
Sequence	MSEEIITPVYCTGVSAQVQKQRARELGLGRHENAIKYLGQDYEQLRVRCLQSGTLFRDEAFPPVPQSLGYKDLGPNSSKTYGIKWKRPTELLSNPQFIVDGATRTDICQGALGDCWLLAAIASLTLNDTLLHRVVPHGQSFQNGYAGIFHFQLWQFGEWVDVVVDDLLPIKDGKLVFVHSAEGNEFWSALLEKAYAKVNGSYEALSGGSTSEGFEDFTGGVTEWYELRKAPSDLYQIILKALERGSLLGCSIDISSVLDMEAITFKKLVKGHAYSVTGAKQVNYRGQVVSLIRMRNPWGEVEWTGAWSDSSSEWNNVDPYERDQLRVKMEDGEFWMSFRDFMREFTRLEICNLTPDALKSRTIRKWNTTLYEGTWRRGSTAGGCRNYPATFWVNPQFKIRLDETDDPDDYGDRESGCSFVLALMQKHRRRERRFGRDMETIGFAVYEVPPELVGQPAVHLKRDFFLANASRARSEQFINLREVSTRFRLPPGEYVVVPSTFEPNKEGDFVLRFFSEKSAGTVELDDQIQANLPDEQVLSEEEIDENFKALFRQLAGEDMEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	451317	CAPN1	calpain 1	9598	VGNC:7514	OMA, EggNOG
Macaque	716618	CAPN1	calpain 1	9544		Inparanoid, OMA, EggNOG
Mouse	12333	Capn1	calpain 1	10090	MGI:88263	Inparanoid, OMA, EggNOG
Rat	29153	Capn1	calpain 1	10116	RGD:2267	Inparanoid, OMA, EggNOG
Dog	483745	CAPN1	calpain 1	9615	VGNC:38698	Inparanoid, OMA
Horse	100051106	CAPN1	calpain 1	9796	VGNC:16037	Inparanoid, OMA
Cow	281661	CAPN1	calpain 1	9913	VGNC:26740	Inparanoid, OMA
Pig	397027	CAPN1	calpain 1	9823		Inparanoid, OMA
Anole lizard	100560015	capn1	calpain 1	28377		Inparanoid, OMA
Xenopus	541455	capn1	calpain 1, (mu/I) large subunit	8364	XB-GENE-990196	Inparanoid, OMA
Zebrafish	565825	si:dkeyp-50d11.2	si:dkeyp-50d11.2	7955	ZDB-GENE-091113-22	Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    calmodulin    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    cysteine protease    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    annexin    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    protease    /    Calpain-1 catalytic subunit
protein    /    calcium-binding protein    /    hydrolase    /    Calpain-1 catalytic subunit

DTO Classes
protein / Enzyme / Protease / Cysteine protease / Calpain-1 catalytic subunit

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

🔙[Back to Target (Human)]

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