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Targets(Human)
CAPN2

CAPN2

Description	Calpain-2 catalytic subunit

Gene and Protein Information

Gene ID	824
Uniprot Accession IDs	P17655 A6NDG7 B7ZA96 E7ES58 Q16738 Q6PJT3 Q8WU26 Q9HBB1
Ensembl ID	ENSG00000162909
Symbol	CANPL2 CANP2 mCANP CANPL2 CANPml
Chromosome	1
Family	Belongs to the peptidase C2 family.
Sequence	MAGIAAKLAKDREAAEGLGSHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	457765	CAPN2	calpain 2	9598	VGNC:6731	OMA, EggNOG
Macaque	703047	CAPN2	calpain 2	9544		Inparanoid, OMA, EggNOG
Mouse	12334	Capn2	calpain 2	10090	MGI:88264	Inparanoid, OMA, EggNOG
Rat	29154	Capn2	calpain 2	10116	RGD:2268	Inparanoid, OMA, EggNOG
Dog	480118	CAPN2	calpain 2	9615	VGNC:53334	Inparanoid, OMA
Horse	100055184	CAPN2	calpain 2	9796	VGNC:49314	Inparanoid, OMA
Cow	281662	CAPN2	calpain 2, (m/II) large subunit	9913		Inparanoid, OMA
Opossum	100018672	CAPN2	calpain 2	13616		Inparanoid, OMA
Platypus	100081577	CAPN2	calpain 2	9258		Inparanoid, OMA
Chicken	395963	CAPN2	calpain 2	9031	CGNC:7115	Inparanoid, OMA
Anole lizard	100561808	capn2	calpain 2	28377		Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    calcium-binding protein    /    calmodulin    /    Calpain-2 catalytic subunit
protein    /    calcium-binding protein    /    cysteine protease    /    Calpain-2 catalytic subunit
protein    /    calcium-binding protein    /    annexin    /    Calpain-2 catalytic subunit
protein    /    calcium-binding protein    /    protease    /    Calpain-2 catalytic subunit
protein    /    calcium-binding protein    /    hydrolase    /    Calpain-2 catalytic subunit

DTO Classes
protein / Enzyme / Protease / Cysteine protease / Calpain-2 catalytic subunit

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

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