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ITCH

Description	E3 ubiquitin-protein ligase Itchy homolog

Gene and Protein Information

Gene ID	83737
Uniprot Accession IDs	Q96J02 A6NEW4 B4E234 E1P5P3 F5H217 O43584 Q5QP37 Q5TEL0 Q96F66 Q9BY75 Q9H451 Q9H4U5 Itch
Ensembl ID	ENSG00000078747
Symbol	AIF4 AIP4 ADMFD NAPP1
Chromosome	20
Sequence	MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNTNSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTLQLGGDKEPTETIGDLSICLDGLQLESEVVTNGETTCSENGVSLCLPRLECNSAISAHCNLCLPGLSDSPISASRVAGFTGASQNDDGSRSKDETRVSTNGSDDPEDAGAGENRRVSGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPPGWEKRTDSNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECDLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYARTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	458191	ITCH	itchy E3 ubiquitin protein ligase	9598	VGNC:6170	Inparanoid, OMA, EggNOG
Macaque	707640	ITCH	itchy E3 ubiquitin protein ligase	9544		Inparanoid, OMA, EggNOG
Mouse	16396	Itch	itchy, E3 ubiquitin protein ligase	10090	MGI:1202301	Inparanoid, OMA, EggNOG
Rat	311567	Itch	itchy E3 ubiquitin protein ligase	10116	RGD:1359556	Inparanoid, OMA
Dog	477199	ITCH	itchy E3 ubiquitin protein ligase	9615	VGNC:42117	Inparanoid, OMA, EggNOG
Horse	100069340	ITCH	itchy E3 ubiquitin protein ligase	9796	VGNC:19157	Inparanoid, OMA, EggNOG
Cow	508431	ITCH	itchy E3 ubiquitin protein ligase	9913	VGNC:30307	Inparanoid, OMA, EggNOG
Opossum	100032356	ITCH	itchy E3 ubiquitin protein ligase	13616		Inparanoid, EggNOG
Platypus		ITCH	itchy E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:13890]	9258		OMA, EggNOG
Anole lizard	100567001	itch	itchy E3 ubiquitin protein ligase	28377		Inparanoid, OMA, EggNOG
Xenopus	780194	itch	itchy E3 ubiquitin protein ligase	8364	XB-GENE-976485	Inparanoid, OMA, EggNOG
C. elegans	171647	wwp-1	E3 ubiquitin-protein ligase	6239		Inparanoid, EggNOG

PANTHER Classes
protein / ligase / ubiquitin-protein ligase / E3 ubiquitin-protein ligase Itchy homolog

DTO Classes
protein / Enzyme / Ligase / Ubiquitin-protein ligase / E3 ubiquitin-protein ligase Itchy homolog

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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