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| Description | Mitogen-activated protein kinase kinase kinase kinase 4 |
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Gene and Protein Information
| Gene ID | 9448 |
|---|---|
| Uniprot Accession IDs | O95819 E7ESS2 O75172 Q9NST7 |
| Ensembl ID | ENSG00000071054 |
| Symbol | HGK KIAA0687 NIK HGK NIK MEKKK4 FLH21957 HEL-S-31 |
| Chromosome | 2 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
| Sequence |
MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEDEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPGHDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDLWSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQRPSTEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSKPSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPADLTALAKELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLSNGETESVKTMIVHDDVESEPAMTPSKEGTLIVRQTQSASSTLQKHKSSSSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRPEAIRQDPTRKGSVVNVNPTNTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQGWTTVGDLEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPKPYHKFMAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 459459 | MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 9598 | VGNC:299 | Inparanoid, OMA, EggNOG |
| Macaque | 716595 | MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 9544 | Inparanoid, OMA | |
| Mouse | 26921 | Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | 10090 | MGI:1349394 | Inparanoid, OMA, EggNOG |
| Rat | 301363 | Map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | 10116 | RGD:1305322 | Inparanoid, OMA, EggNOG |
| Dog | 481331 | MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 9615 | VGNC:42984 | Inparanoid, OMA |
| Horse | 100058919 | MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 9796 | VGNC:19948 | Inparanoid, OMA |
| Opossum | 100017539 | MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 13616 | Inparanoid, OMA | |
| Anole lizard | 100567473 | map4k4 | mitogen-activated protein kinase kinase kinase kinase 4 | 28377 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE20 family / MSN subfamily / Mitogen-activated protein kinase kinase kinase kinase 4
protein / Kinase / Protein kinase / STE group / STE20 family / MSN subfamily / Mitogen-activated protein kinase kinase kinase kinase 4
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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