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| Description | Mitogen-activated protein kinase kinase kinase 1 |
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Gene and Protein Information
| Gene ID | 4214 |
|---|---|
| Uniprot Accession IDs | Q13233 |
| Ensembl ID | ENSG00000095015 |
| Symbol | MAPKKK1 MEKK MEKK1 MEKK MEKK1 SRXY6 MEKK 1 MAPKKK1 |
| Chromosome | 5 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. |
| Sequence |
MAAAAGNRASSSGFPGARATSPEAGGGGGALKASSAPAAAAGLLREAGSGGRERADWRRRQLRKVRSVELDQLPEQPLFLAASPPASSTSPSPEPADAAGSGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGASSPAAAEPGEKRAPAAEPSPAAAPAGREMENKETLKGLHKMDDRPEERMIREKLKATCMPAWKHEWLERRNRRGPVVVKPIPVKGDGSEMNHLAAESPGEVQASAASPASKGRRSPSPGNSPSGRTVKSESPGVRRKRVSPVPFQSGRITPPRRAPSPDGFSPYSPEETNRRVNKVMRARLYLLQQIGPNSFLIGGDSPDNKYRVFIGPQNCSCARGTFCIHLLFVMLRVFQLEPSDPMLWRKTLKNFEVESLFQKYHSRRSSRIKAPSRNTIQKFVSRMSNSHTLSSSSTSTSSSENSIKDEEEQMCPICLLGMLDEESLTVCEDGCRNKLHHHCMSIWAEECRRNREPLICPLCRSKWRSHDFYSHELSSPVDSPSSLRAAQQQTVQQQPLAGSRRNQESNFNLTHYGTQQIPPAYKDLAEPWIQVFGMELVGCLFSRNWNVREMALRRLSHDVSGALLLANGESTGNSGGSSGSSPSGGATSGSSQTSISGDVVEACCSVLSMVCADPVYKVYVAALKTLRAMLVYTPCHSLAERIKLQRLLQPVVDTILVKCADANSRTSQLSISTLLELCKGQAGELAVGREILKAGSIGIGGVDYVLNCILGNQTESNNWQELLGRLCLIDRLLLEFPAEFYPHIVSTDVSQAEPVEIRYKKLLSLLTFALQSIDNSHSMVGKLSRRIYLSSARMVTTVPHVFSKLLEMLSVSSSTHFTRMRRRLMAIADEVEIAEAIQLGVEDTLDGQQDSFLQASVPNNYLETTENSSPECTVHLEKTGKGLCATKLSASSEDISERLASISVGPSSSTTTTTTTTEQPKPMVQTKGRPHSQCLNSSPLSHHSQLMFPALSTPSSSTPSVPAGTATDVSKHRLQGFIPCRIPSASPQTQRKFSLQFHRNCPENKDSDKLSPVFTQSRPLPSSNIHRPKPSRPTPGNTSKQGDPSKNSMTLDLNSSSKCDDSFGCSSNSSNAVIPSDETVFTPVEEKCRLDVNTELNSSIEDLLEASMPSSDTTVTFKSEVAVLSPEKAENDDTYKDDVNHNQKCKEKMEAEEEEALAIAMAMSASQDALPIVPQLQVENGEDIIIIQQDTPETLPGHTKAKQPYREDTEWLKGQQIGLGAFSSCYQAQDVGTGTLMAVKQVTYVRNTSSEQEEVVEALREEIRMMSHLNHPNIIRMLGATCEKSNYNLFIEWMAGGSVAHLLSKYGAFKESVVINYTEQLLRGLSYLHENQIIHRDVKGANLLIDSTGQRLRIADFGAAARLASKGTGAGEFQGQLLGTIAFMAPEVLRGQQYGRSCDVWSVGCAIIEMACAKPPWNAEKHSNHLALIFKIASATTAPSIPSHLSPGLRDVALRCLELQPQDRPPSRELLKHPVFRTTW
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 471543 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9598 | VGNC:8626 | OMA, EggNOG |
| Macaque | 710979 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9544 | Inparanoid, OMA | |
| Mouse | 26401 | Map3k1 | mitogen-activated protein kinase kinase kinase 1 | 10090 | MGI:1346872 | Inparanoid, OMA, EggNOG |
| Rat | 116667 | Map3k1 | mitogen-activated protein kinase kinase kinase 1 | 10116 | RGD:620966 | Inparanoid, OMA, EggNOG |
| Dog | 478061 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9615 | VGNC:42966 | Inparanoid, OMA, EggNOG |
| Horse | 100061688 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9796 | VGNC:19930 | Inparanoid, OMA, EggNOG |
| Cow | 523962 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9913 | VGNC:31188 | Inparanoid, OMA, EggNOG |
| Pig | 396617 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | 100032065 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 13616 | Inparanoid, OMA, EggNOG | |
| Platypus | 100076612 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9258 | Inparanoid, OMA, EggNOG | |
| Chicken | 427144 | MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 9031 | CGNC:10913 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100561745 | map3k1 | mitogen-activated protein kinase kinase kinase 1 | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | map3k1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase [Source:Xenbase;Acc:XB-GENE-1008434] | 8364 | OMA, EggNOG | ||
| Zebrafish | 100334486 | map3k1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 7955 | ZDB-GENE-090313-412 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE11 family / Mitogen-activated protein kinase kinase kinase 1
protein / Kinase / Protein kinase / STE group / STE11 family / Mitogen-activated protein kinase kinase kinase 1
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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