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| Description | Mitogen-activated protein kinase kinase kinase 10 |
|---|
Gene and Protein Information
| Gene ID | 4294 |
|---|---|
| Uniprot Accession IDs | Q02779 Q12761 Q14871 |
| Ensembl ID | ENSG00000130758 |
| Symbol | MLK2 MST MST MLK2 MEKK10 |
| Chromosome | 19 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. |
| Sequence |
MEEEEGAVAKEWGTTPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWTGQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGEEVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEECWDPDPHGRPDFGSILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQRFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKRKGNFKRSRLLKLREGGSHISLPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSSGGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSSAPNLGKSPKHTPIAPGFASLNEMEEFAEAEDGGSSVPPSPYSTPSYLSVPLPAEPSPGARAPWEPTPSAPPARWGHGARRRCDLALLGCATLLGAVGLGADVAEARAADGEEQRRWLDGLFFPRAGRFPRGLSPPARPHGRREDVGPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPAAPSPPPSPPAPTPTPSPSTNPLVDLELESFKKDPRQSLTPTHVTAACAVSRGHRRTPSDGALGQRGPPEPAGHGPGPRDLLDFPRLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAASRPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSVQPTLLDMDMEGQNQDSTVPLCGAHGSH
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 468880 | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 9598 | VGNC:11235 | OMA, EggNOG |
| Macaque | 700477 | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 9544 | Inparanoid, OMA, EggNOG | |
| Mouse | 269881 | Map3k10 | mitogen-activated protein kinase kinase kinase 10 | 10090 | MGI:1346879 | Inparanoid, OMA, EggNOG |
| Rat | 308463 | Map3k10 | mitogen activated protein kinase kinase kinase 10 | 10116 | RGD:1308381 | Inparanoid, OMA, EggNOG |
| Dog | 484504 | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 9615 | VGNC:53748 | Inparanoid, OMA, EggNOG |
| Cow | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 [Source:HGNC Symbol;Acc:HGNC:6849] | 9913 | OMA, EggNOG | ||
| Pig | 100521453 | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 9823 | OMA, EggNOG | |
| Opossum | 100017495 | MAP3K10 | mitogen-activated protein kinase kinase kinase 10 | 13616 | Inparanoid, OMA, EggNOG | |
| Anole lizard | 100565973 | map3k10 | mitogen-activated protein kinase kinase kinase 10 | 28377 | Inparanoid, OMA | |
| Xenopus | 100488058 | map3k10 | mitogen-activated protein kinase kinase kinase 10 | 8364 | XB-GENE-920944 | Inparanoid, OMA |
| Zebrafish | 560932 | map3k10 | mitogen-activated protein kinase kinase kinase 10 | 7955 | ZDB-GENE-050419-112 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / TKL group / MLK family / MLK subfamily / Mitogen-activated protein kinase kinase kinase 10
protein / Kinase / Protein kinase / TKL group / MLK family / MLK subfamily / Mitogen-activated protein kinase kinase kinase 10
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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