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GAA

Description	Lysosomal alpha-glucosidase

Gene and Protein Information

Gene ID	2548
Uniprot Accession IDs	P10253 Q09GN4 Q14351 Q16302 Q8IWE7
Ensembl ID	ENSG00000171298
Symbol	LYAG
Chromosome	17
Family	Belongs to the glycosyl hydrolase 31 family.
Sequence	MGVRHPPCSHRLLAVCALVSLATAALLGHILLHDFLLVPRELSGSSPVLEETHPAHQQGASRPGPRDAQAHPGRPRAVPTQCDVPPNSRFDCAPDKAITQEQCEARGCCYIPAKQGLQGAQMGQPWCFFPPSYPSYKLENLSSSEMGYTATLTRTTPTFFPKDILTLRLDVMMETENRLHFTIKDPANRRYEVPLETPHVHSRAPSPLYSVEFSEEPFGVIVRRQLDGRVLLNTTVAPLFFADQFLQLSTSLPSQYITGLAEHLSPLMLSTSWTRITLWNRDLAPTPGANLYGSHPFYLALEDGGSAHGVFLLNSNAMDVVLQPSPALSWRSTGGILDVYIFLGPEPKSVVQQYLDVVGYPFMPPYWGLGFHLCRWGYSSTAITRQVVENMTRAHFPLDVQWNDLDYMDSRRDFTFNKDGFRDFPAMVQELHQGGRRYMMIVDPAISSSGPAGSYRPYDEGLRRGVFITNETGQPLIGKVWPGSTAFPDFTNPTALAWWEDMVAEFHDQVPFDGMWIDMNEPSNFIRGSEDGCPNNELENPPYVPGVVGGTLQAATICASSHQFLSTHYNLHNLYGLTEAIASHRALVKARGTRPFVISRSTFAGHGRYAGHWTGDVWSSWEQLASSVPEILQFNLLGVPLVGADVCGFLGNTSEELCVRWTQLGAFYPFMRNHNSLLSLPQEPYSFSEPAQQAMRKALTLRYALLPHLYTLFHQAHVAGETVARPLFLEFPKDSSTWTVDHQLLWGEALLITPVLQAGKAEVTGYFPLGTWYDLQTVPVEALGSLPPPPAAPREPAIHSEGQWVTLPAPLDTINVHLRAGYIIPLQGPGLTTTESRQQPMALAVALTKGGEARGELFWDDGESLEVLERGAYTQVIFLARNNTIVNELVRVTSEGAGLQLQKVTVLGVATAPQQVLSNGVPVSNFTYSPDTKVLDICVSLLMGEQFLVSWC Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	454940	GAA	glucosidase alpha, acid	9598	VGNC:9298	OMA, EggNOG
Macaque	712054	GAA	glucosidase alpha, acid	9544		Inparanoid, OMA, EggNOG
Mouse	14387	Gaa	glucosidase, alpha, acid	10090	MGI:95609	Inparanoid, OMA, EggNOG
Rat	367562	Gaa	glucosidase, alpha, acid	10116	RGD:735227	Inparanoid, OMA, EggNOG
Dog	483352	GAA	glucosidase alpha, acid	9615	VGNC:41044	Inparanoid, OMA, EggNOG
Horse	100056675	GAA	glucosidase alpha, acid	9796	VGNC:18184	Inparanoid, OMA, EggNOG
Cow	280798	GAA	glucosidase alpha, acid	9913	VGNC:29182	Inparanoid, OMA, EggNOG
Pig	100526132	GAA	glucosidase alpha, acid	9823		OMA, EggNOG
Opossum	100030818	GAA	glucosidase alpha, acid	13616		Inparanoid, OMA, EggNOG
Platypus		GAA	glucosidase alpha, acid [Source:HGNC Symbol;Acc:HGNC:4065]	9258		OMA, EggNOG
Anole lizard	100561813	gaa	glucosidase alpha, acid	28377		Inparanoid, OMA
Xenopus		gaa	glucosidase, alpha; acid [Source:Xenbase;Acc:XB-GENE-6054131]	8364		OMA, EggNOG
Zebrafish	100002366	gaa	glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II)	7955	ZDB-GENE-070212-2	Inparanoid, OMA, EggNOG

PANTHER Classes
protein / hydrolase / glucosidase / Lysosomal alpha-glucosidase

DTO Classes
protein / Enzyme / Hydrolase / Glucosidase / Lysosomal alpha-glucosidase

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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