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LIPA

Description Lysosomal acid lipase/cholesteryl ester hydrolase

Gene and Protein Information

Gene ID 3988
Uniprot Accession IDs P38571 B2RBH5 D3DR29 Q16529 Q53H21 Q5T074 Q5T771 Q96EJ0 Acid cholesteryl ester hydrolase
Ensembl ID ENSG00000107798
Symbol LAL CESD
Chromosome 10
Family Belongs to the AB hydrolase superfamily. Lipase family.
Sequence
MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 466150 LIPA lipase A, lysosomal acid type 9598 VGNC:7847 OMA, EggNOG
Mouse 16889 Lipa lysosomal acid lipase A 10090 MGI:96789 Inparanoid, OMA, EggNOG
Rat 25055 Lipa lipase A, lysosomal acid type 10116 RGD:3008 Inparanoid, OMA, EggNOG
Dog 100856363 LIPA lipase A, lysosomal acid type 9615 VGNC:42693 Inparanoid, OMA, EggNOG
Horse 100071626 LIPA lipase A, lysosomal acid type 9796 VGNC:19685 Inparanoid, OMA, EggNOG
Cow 100125267 LIPA lipase A, lysosomal acid type 9913 VGNC:30904 Inparanoid, OMA, EggNOG
Pig 100142668 LIPA lipase A, lysosomal acid type 9823 Inparanoid, OMA, EggNOG
Chicken 423789 LIPA lipase A, lysosomal acid type 9031 CGNC:4801 Inparanoid, OMA
Zebrafish 406713 lipf lipase, gastric 7955 ZDB-GENE-040426-2737 Inparanoid, OMA

Protein Classes

PANTHER Classes
protein    /    hydrolase    /    serine protease    /    Lysosomal acid lipase/cholesteryl ester hydrolase
protein    /    hydrolase    /    lipase    /    Lysosomal acid lipase/cholesteryl ester hydrolase
DTO Classes
protein    /    Enzyme    /    Hydrolase    /    Lipase    /    Lysosomal acid lipase/cholesteryl ester hydrolase

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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