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LEFTY2

Description Left-right determination factor 2

Gene and Protein Information

Gene ID 7044
Uniprot Accession IDs O00292 B3KNH4 B4E332 E9PDM4 O75611 Q5TE89 Q8NBQ9
Ensembl ID ENSG00000143768
Symbol EBAF LEFTA LEFTYA TGFB4 EBAF LEFTA TGFB4 LEFTYA
Chromosome 1
Family Belongs to the TGF-beta family.
Sequence
MWPLWLCWALWVLPLAGPGAALTEEQLLGSLLRQLQLSEVPVLDRADMEKLVIPAHVRAQYVVLLRRSHGDRSRGKRFSQSFREVAGRFLASEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSAQARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLRDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQGMKWAKNWVLEPPGFLAYECVGTCQQPPEALAFNWPFLGPRQCIASETASLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRRLQP
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 457780 LEFTY2 left-right determination factor 2 9598 VGNC:8063 OMA, EggNOG
Mouse 13590 Lefty1 left right determination factor 1 10090 MGI:107405 Inparanoid, OMA, EggNOG
Rat 498299 Lefty1 left right determination factor 1 10116 RGD:1561867 Inparanoid, OMA, EggNOG
Dog 490387 LOC490387 left-right determination factor 1 9615 OMA, EggNOG
Horse 100054366 LOC100054366 left-right determination factor 1-like 9796 OMA, EggNOG
Cow 100336971 LOC100336971 left-right determination factor 2-like 9913 OMA, EggNOG
Opossum 100025872 LOC100025872 left-right determination factor 2 13616 OMA, EggNOG
Platypus 100082000 LOC100082000 left-right determination factor 1 9258 Inparanoid, OMA, EggNOG
Anole lizard 100555191 LOC100555191 left-right determination factor 2-like 28377 OMA, EggNOG
Zebrafish 30146 lft2 lefty2 7955 ZDB-GENE-990630-11 OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    signaling molecule    /    growth factor    /    Left-right determination factor 2
DTO Classes
protein    /    Signaling    /    Growth factor    /    Left-right determination factor 2

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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