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| Description | Leptin receptor |
|---|
Gene and Protein Information
| Gene ID | 3953 |
|---|---|
| Uniprot Accession IDs | P48357 Q13592 Q13593 Q13594 Q92919 Q92920 Q92921 LEP-R |
| Ensembl ID | ENSG00000116678 |
| Symbol | DB OBR OBR OB-R CD295 LEP-R LEPRD |
| Chromosome | 1 |
| Family | Belongs to the type I cytokine receptor family. Type 2 subfamily. |
| Sequence |
MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVFQQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFASYMPQFQTCSTQTHKIMENKMCDLTV
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 456919 | LEPR | leptin receptor | 9598 | VGNC:1296 | OMA, EggNOG |
| Macaque | 574126 | LEPR | leptin receptor | 9544 | Inparanoid, OMA | |
| Mouse | 16847 | Lepr | leptin receptor | 10090 | MGI:104993 | Inparanoid, OMA, EggNOG |
| Rat | 24536 | Lepr | leptin receptor | 10116 | RGD:3001 | Inparanoid, OMA |
| Dog | 450207 | LEPR | leptin receptor | 9615 | VGNC:42638 | Inparanoid, OMA, EggNOG |
| Horse | 100069504 | LEPR | leptin receptor | 9796 | VGNC:19633 | Inparanoid, OMA, EggNOG |
| Cow | 497205 | LEPR | leptin receptor | 9913 | VGNC:30843 | OMA, EggNOG |
| Pig | 396836 | LEPR | leptin receptor | 9823 | Inparanoid, OMA, EggNOG | |
| Opossum | LEPR | leptin receptor [Source:HGNC Symbol;Acc:HGNC:6554] | 13616 | Inparanoid, OMA, EggNOG | ||
| Platypus | LEPR | leptin receptor [Source:HGNC Symbol;Acc:HGNC:6554] | 9258 | OMA, EggNOG | ||
| Chicken | 374223 | LEPR | leptin receptor | 9031 | CGNC:49091 | Inparanoid, OMA, EggNOG |
| Anole lizard | 100558934 | lepr | leptin receptor | 28377 | Inparanoid, OMA, EggNOG | |
| Xenopus | 724071 | lepr | leptin receptor | 8364 | XB-GENE-980270 | Inparanoid, OMA, EggNOG |
| Zebrafish | 567241 | lepr | leptin receptor | 7955 | ZDB-GENE-080104-1 | Inparanoid, OMA, EggNOG |
Protein Classes
PANTHER Classes
protein / signaling molecule / defense/immunity protein / Leptin receptor
protein / signaling molecule / cytokine / Leptin receptor
protein / signaling molecule / defense/immunity protein / Leptin receptor
protein / signaling molecule / cytokine / Leptin receptor
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
|---|
Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
|---|
Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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