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| Description | Mitogen-activated protein kinase kinase kinase kinase 2 |
|---|
Gene and Protein Information
| Gene ID | 5871 |
|---|---|
| Uniprot Accession IDs | Q12851 Q86VU3 |
| Ensembl ID | ENSG00000168067 |
| Symbol | GCK RAB8IP GCK BL44 RAB8IP |
| Chromosome | 11 |
| Family | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. |
| Sequence |
MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASDPHLGTPSPEDCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEPLSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNGCPLRIHAAVTWIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGATFLLAALPTSLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKELPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTILVSFERCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY
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Homologous gene and protein info.
| Species | Gene ID | Gene Symbol | Name | Tax ID | Other Gene ID | Sources |
|---|---|---|---|---|---|---|
| Chimp | 451301 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 9598 | VGNC:7507 | OMA, EggNOG |
| Macaque | 699331 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 9544 | OMA, EggNOG | |
| Mouse | 26412 | Map4k2 | mitogen-activated protein kinase kinase kinase kinase 2 | 10090 | MGI:1346883 | Inparanoid, OMA, EggNOG |
| Rat | 293694 | Map4k2 | mitogen activated protein kinase kinase kinase kinase 2 | 10116 | RGD:1308199 | Inparanoid, OMA |
| Dog | 483759 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 9615 | VGNC:42982 | Inparanoid, OMA |
| Horse | 100056001 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 9796 | VGNC:19946 | Inparanoid, OMA |
| Cow | 520058 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 9913 | VGNC:31205 | Inparanoid, OMA |
| Pig | 100523716 | MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 | 9823 | Inparanoid, OMA | |
| C. elegans | 179072 | gck-2 | Mitogen-activated protein kinase kinase kinase kinase | 6239 | Inparanoid, OMA |
Protein Classes
DTO Classes
protein / Kinase / Protein kinase / STE group / STE20 family / KHS subfamily / Mitogen-activated protein kinase kinase kinase kinase 2
protein / Kinase / Protein kinase / STE group / STE20 family / KHS subfamily / Mitogen-activated protein kinase kinase kinase kinase 2
Associated Recombinant Proteins
| Name | Specification and purity | Expression system | Protein label | Availability | View Details |
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Associated Antibodies
| Name | Specifications | Species reactivity | Application | Availability | View Details |
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Associated Approved Drugs
Associated Active Ligands
Associated Diseases
| Name | Direct Associated Targets | Disease Type | Mondoid |
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Bibliography
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