EEF2

Description	Elongation factor 2

Gene and Protein Information

Gene ID	1938
Uniprot Accession IDs	P13639 B2RMP5 D6W618 Q58J86 EF-2
Ensembl ID	ENSG00000167658
Symbol	EF2 EF2 EF-2 EEF-2 SCA26
Chromosome	19
Family	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Sequence	MVNFTVDQIRAIMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFYELSENDLNFIKQSKDGAGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIISTYGEGESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGPAERAKKVEDMMKKLWGDRYFDPANGKFSKSATSPEGKKLPRTFCQLILDPIFKVFDAIMNFKKEETAKLIEKLDIKLDSEDKDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSDKGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLVKTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETVSEESNVLCLSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSARQELKQRARYLAEKYEWDVAEARKIWCFGPDGTGPNILTDITKGVQYLNEIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHADAIHRGGGQIIPTARRCLYASVLTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVFDHWQILPGDPFDNSSRPSQVVAETRKRKGLKEGIPALDNFLDKL Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	100614367	EEF2	eukaryotic translation elongation factor 2	9598		OMA, EggNOG
Macaque	721806	EEF2	eukaryotic translation elongation factor 2	9544		Inparanoid, OMA, EggNOG
Mouse	13629	Eef2	eukaryotic translation elongation factor 2	10090	MGI:95288	Inparanoid, OMA, EggNOG
Rat	29565	Eef2	eukaryotic translation elongation factor 2	10116	RGD:61979	Inparanoid, OMA, EggNOG
Dog	476744	EEF2	eukaryotic translation elongation factor 2	9615	VGNC:40209	Inparanoid, OMA, EggNOG
Horse	100061437	EEF2	eukaryotic translation elongation factor 2	9796	VGNC:17432	Inparanoid, OMA, EggNOG
Cow	281138	EEF2	eukaryotic translation elongation factor 2	9913	VGNC:28335	Inparanoid, OMA, EggNOG
Pig	100624328	EEF2	eukaryotic translation elongation factor 2	9823		Inparanoid, OMA, EggNOG
Opossum	100022172	EEF2	eukaryotic translation elongation factor 2	13616		Inparanoid, OMA
Platypus		EEF2	eukaryotic translation elongation factor 2 [Source:HGNC Symbol;Acc:HGNC:3214]	9258		OMA, EggNOG
Anole lizard	100565477	eef2	eukaryotic translation elongation factor 2	28377		Inparanoid, OMA, EggNOG
Xenopus	394866	eef2.1	eukaryotic translation elongation factor 2, gene 1	8364	XB-GENE-969739	Inparanoid, OMA, EggNOG
Zebrafish	336168	eef2l2	eukaryotic translation elongation factor 2, like 2	7955	ZDB-GENE-030131-8112	OMA, EggNOG
C. elegans	172743	eef-2	Elongation factor 2	6239		Inparanoid, OMA
Fruitfly	35422	EF2	Elongation factor 2	7227	FBgn0000559	Inparanoid, OMA, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    translation initiation factor    /    Elongation factor 2
protein    /    nucleic acid binding    /    translation elongation factor    /    Elongation factor 2
protein    /    nucleic acid binding    /    hydrolase    /    Elongation factor 2
protein    /    nucleic acid binding    /    G-protein    /    Elongation factor 2

DTO Classes
protein / Enzyme / Hydrolase / Elongation factor 2

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography