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Targets(Human)
KDM1A

KDM1A

Description	Lysine-specific histone demethylase 1A

Gene and Protein Information

Gene ID	23028
Uniprot Accession IDs	O60341 A8MWP9 Q5TH94 Q5TH95 Q86VT7 Q8IXK4 Q8NDP6 Q8TAZ3 Q96AW4
Ensembl ID	ENSG00000004487
Symbol	AOF2 KDM1 KIAA0601 LSD1 AOF2 CPRF KDM1 LSD1 BHC110
Chromosome	1
Family	Belongs to the flavin monoamine oxidase family.
Sequence	MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPSM Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	456614	KDM1A	lysine demethylase 1A	9598	VGNC:8065	OMA, EggNOG
Macaque	718609	KDM1A	lysine demethylase 1A	9544		Inparanoid, OMA, EggNOG
Mouse	99982	Kdm1a	lysine (K)-specific demethylase 1A	10090	MGI:1196256	Inparanoid, OMA, EggNOG
Rat	500569	Kdm1a	lysine demethylase 1A	10116	RGD:1562975	Inparanoid, OMA
Dog	478193	KDM1A	lysine demethylase 1A	9615	VGNC:42318	Inparanoid, OMA, EggNOG
Horse	100071646	KDM1A	lysine demethylase 1A	9796	VGNC:19331	Inparanoid, OMA, EggNOG
Cow	532997	KDM1A	lysine demethylase 1A	9913	VGNC:30522	Inparanoid, OMA, EggNOG
Pig	100127157	KDM1A	lysine demethylase 1A	9823		Inparanoid, OMA, EggNOG
Opossum	100025161	KDM1A	lysine demethylase 1A	13616		Inparanoid, OMA, EggNOG
Platypus		KDM1A	lysine demethylase 1A [Source:HGNC Symbol;Acc:HGNC:29079]	9258		OMA, EggNOG
Anole lizard	100557968	kdm1a	lysine demethylase 1A	28377		Inparanoid, OMA, EggNOG
Xenopus	100216250	kdm1a	lysine (K)-specific demethylase 1A	8364	XB-GENE-5816927	Inparanoid, OMA, EggNOG
Zebrafish	558450	kdm1a	lysine (K)-specific demethylase 1a	7955	ZDB-GENE-030131-7828	Inparanoid, OMA, EggNOG
Fruitfly	40217	Su(var)3-3	Suppressor of variegation 3-3	7227	FBgn0260397	Inparanoid, EggNOG

Protein Classes

PANTHER Classes
protein    /    nucleic acid binding    /    oxidase    /    Lysine-specific histone demethylase 1A
protein    /    nucleic acid binding    /    DNA binding protein    /    Lysine-specific histone demethylase 1A
protein    /    nucleic acid binding    /    methyltransferase    /    Lysine-specific histone demethylase 1A
protein    /    nucleic acid binding    /    DNA methyltransferase    /    Lysine-specific histone demethylase 1A

DTO Classes
protein / Epigenetic regulator / Eraser / Lysine demethylase / Lysine-specific demethylase / Lysine-specific histone demethylase 1A

Associated Recombinant Proteins

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Associated Antibodies

Name	Specifications	Species reactivity	Application	Availability	View Details

Related active small molecules

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name	Direct Associated Targets	Disease Type	Mondoid

Bibliography

🔙[Back to Target (Human)]

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