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PRAME

Description Melanoma antigen preferentially expressed in tumors

Gene and Protein Information

Gene ID 23532
Uniprot Accession IDs P78395 B2R6Y7 O43481 Q8IXN8
Ensembl ID ENSG00000185686
Symbol MAPE OIP4 MAPE OIP4 CT130 OIP-4
Chromosome 22
Family Belongs to the PRAME family.
Sequence
MERRRLWGSIQSRYISMSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFYDPEPILCPCFMPN
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Homologous gene and protein info.
Species Gene ID Gene Symbol Name Tax ID Other Gene ID Sources
Chimp 470260 PRAME preferentially expressed antigen in melanoma 9598 OMA, EggNOG
Macaque 700564 LOC700564 melanoma antigen preferentially expressed in tumors 9544 OMA, EggNOG
Dog 477552 PRAME preferentially expressed antigen in melanoma 9615 Inparanoid, OMA, EggNOG
Horse 100061889 LOC100061889 melanoma antigen preferentially expressed in tumors 9796 OMA, EggNOG
Cow 789301 LOC789301 melanoma antigen preferentially expressed in tumors-like 9913 OMA, EggNOG

Associated Recombinant Proteins

Name Specification and purity Expression system Protein label Availability View Details

Associated Antibodies

Name Specifications Species reactivity Application Availability View Details

Associated Approved Drugs

Associated Active Ligands

Associated Diseases

Name Direct Associated Targets Disease Type Mondoid

Bibliography

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