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PLK1

Description	Serine/threonine-protein kinase PLK1

Gene and Protein Information

Gene ID	5347
Uniprot Accession IDs	P53350 Q15153 Q99746
Ensembl ID	ENSG00000166851
Symbol	PLK PLK STPK13
Chromosome	16
Family	Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
Sequence	MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS Show more

Homologous gene and protein info.

Species	Gene ID	Gene Symbol	Name	Tax ID	Other Gene ID	Sources
Chimp	453991	PLK1	polo like kinase 1	9598	VGNC:8992	Inparanoid, OMA, EggNOG
Macaque	697686	PLK1	polo like kinase 1	9544		Inparanoid, EggNOG
Mouse	18817	Plk1	polo like kinase 1	10090	MGI:97621	Inparanoid, OMA, EggNOG
Rat	25515	Plk1	polo-like kinase 1	10116	RGD:3352	Inparanoid, OMA, EggNOG
Dog	489971	PLK1	polo like kinase 1	9615	VGNC:44695	Inparanoid, OMA, EggNOG
Horse	100068388	PLK1	polo like kinase 1	9796	VGNC:21579	Inparanoid, OMA, EggNOG
Cow	538238	PLK1	polo like kinase 1	9913	VGNC:33033	Inparanoid, OMA, EggNOG
Pig	396953	PLK1	polo like kinase 1	9823		Inparanoid, OMA, EggNOG
Opossum	100027403	PLK1	polo like kinase 1	13616		Inparanoid, OMA, EggNOG
Platypus	100073533	PLK1	polo like kinase 1	9258		Inparanoid, OMA, EggNOG
Chicken	416575	PLK1	polo like kinase 1	9031	CGNC:4585	Inparanoid, OMA, EggNOG
Anole lizard	100558384	plk1	polo like kinase 1	28377		Inparanoid, OMA, EggNOG
Xenopus	407937	plk1	polo like kinase 1	8364	XB-GENE-941540	Inparanoid, OMA, EggNOG
Zebrafish	280649	plk1	polo-like kinase 1 (Drosophila)	7955	ZDB-GENE-021115-7	Inparanoid, OMA, EggNOG
C. elegans	176143	plk-1	Serine/threonine-protein kinase plk-1	6239		OMA, EggNOG
C. elegans	171838	plk-2	Serine/threonine-protein kinase plk-2	6239		Inparanoid, OMA
Fruitfly	40232	polo	CG12306 gene product from transcript CG12306-RA	7227	FBgn0003124	Inparanoid, OMA, EggNOG
S.cerevisiae	855013	CDC5	polo kinase CDC5	4932	S000004603	OMA, EggNOG

DTO Classes
protein / Kinase / Protein kinase / Other group / PLK family / Serine/threonine-protein kinase plk1

Name	Specification and purity	Expression system	Protein label	Availability	View Details

Name	Specifications	Species reactivity	Application	Availability	View Details

AntibodiesProductName	Specification and purity	Mechanism Of Action	Availability	View Details

Name	Direct Associated Targets	Disease Type	Mondoid

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