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T22, Antagonist of CXCR4, CAS No.147658-54-6, Antagonist of CXCR4

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rp175256
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rp175256-500μg
500μg
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$1,334.90
rp175256-1mg
1mg
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Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90
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Basic Description

Product Name T22, Antagonist of CXCR4, CAS No.147658-54-6
Synonyms [Tyr⁵'¹²,Lys⁷]-polyphemusin II
Grade Moligand™
Specifications & Purity Moligand™
Action Type ANTAGONIST
Mechanism of action Antagonist of CXCR4

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic Polymers
Class Polypeptides
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Polypeptides
Alternative Parents Cyclic peptides  Arginine and derivatives  N-acyl-alpha amino acids and derivatives  Macrolactams  Tryptamines and derivatives  Alpha amino acid amides  3-alkylindoles  1-hydroxy-2-unsubstituted benzenoids  Substituted pyrroles  Benzene and substituted derivatives  N-acyl amines  Heteroaromatic compounds  Secondary carboxylic acid amides  Primary carboxylic acid amides  Lactams  Organic disulfides  Guanidines  Azacyclic compounds  Carboximidamides  Carbonyl compounds  Hydrocarbon derivatives  Imines  Monoalkylamines  Organic oxides  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Polypeptide - Cyclic alpha peptide - Arginine or derivatives - Macrolactam - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Triptan - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - 3-alkylindole - Indole - Indole or derivatives - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Fatty amide - Fatty acyl - N-acyl-amine - Benzenoid - Substituted pyrrole - Pyrrole - Heteroaromatic compound - Amino acid or derivatives - Secondary carboxylic acid amide - Organic disulfide - Primary carboxylic acid amide - Carboxamide group - Lactam - Guanidine - Carboximidamide - Organoheterocyclic compound - Azacycle - Carboxylic acid derivative - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Imine - Organic oxide - Carbonyl group - Organic nitrogen compound - Primary amine - Primary aliphatic amine - Amine - Organonitrogen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors Not available

Associated Targets(Human)

CXCR4 Tclin C-X-C chemokine receptor type 4 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Storage and Shipping

CAS 147658-54-6

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names [Tyr⁵'¹²,Lys⁷]-polyphemusin II
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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