Red fluorophore standard for neurological staining and enzyme assays. Used as polar tracers for the studies of neuronal cell morphology and cell-cell communications.
Storage Temp
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Note
Refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Sulforhodamine 101 is a red emitting fluorophore with an extinction coefficient of 105000. Sulforhodamine 101 is ideally used to label astrocytes in the rodent neocortex which can be observed with two-photon microscopy. In addition, Sulforhodamine 101 is used to determine morphological characteristics of astrocytes and to observe the association of astrocytes with the cortical microvasculature. Furthermore, this fluorophore is used as an activity-dependent dye for monitoring regulated exocytosis. Alternate studies suggest that Sulforhodamine 101 can increase intrinsic neuronal excitability and long-lasting increases in evoked EPSCs in CA1 pyramidal neurons in hippocampal slices. Sulforhodamine 101 enhances evoked synaptic N-methyl D-aspartate receptor (NMDAR) currents which can be blocked by the antagonist, AP-5. A red-emitting flurophore used to label astrocytes.
This compound belongs to the class of organic compounds known as xanthenes. These are polycyclic aromatic compounds containing a xanthene moiety, which consists of two benzene rings joined to each other by a pyran ring.
External Descriptors
organic heteroheptacyclic compound
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
5 Citations
C2506691