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Sulfopin - 10mM in DMSO, high purity , CAS No.2451481-08-4(DMSO), Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1
Basic Description
| Synonyms |
2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide | HY-139361 | Z3375875148 | 2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxo-1lambda6-thiolan-3-yl)acetamide | EN300-6495949 | 2451481-08-4 | AKOS040759747 | PIN1-3 | CS-0198725 | GTPL11540 | |
| Specifications & Purity |
Moligand™, 10mM in DMSO |
| Storage Temp |
Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade |
Moligand™ |
| Action Type |
INHIBITOR |
| Mechanism of action |
Inhibitor of peptidylprolyl cis/trans isomerase; NIMA-interacting 1 |
| Product Description |
Product description：
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo. |
Associated Targets(Human)
Names and Identifiers
| IUPAC Name |
2-chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide |
| INCHI |
InChI=1S/C11H20ClNO3S/c1-11(2,3)8-13(10(14)6-12)9-4-5-17(15,16)7-9/h9H,4-8H2,1-3H3 |
| InChIKey |
NMHVAHHYKGXBMY-UHFFFAOYSA-N |
| Smiles |
CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl |
| Isomeric SMILES |
CC(C)(C)CN(C1CCS(=O)(=O)C1)C(=O)CCl |
| PubChem CID |
155804394 |
| Molecular Weight |
281.8 |
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
Chemical and Physical Properties
| Molecular Weight |
281.800 g/mol |
| XLogP3 |
1.600 |
| Hydrogen Bond Donor Count |
0 |
| Hydrogen Bond Acceptor Count |
3 |
| Rotatable Bond Count |
4 |
| Exact Mass |
281.085 Da |
| Monoisotopic Mass |
281.085 Da |
| Topological Polar Surface Area |
62.800 Ų |
| Heavy Atom Count |
17 |
| Formal Charge |
0 |
| Complexity |
381.000 |
| Isotope Atom Count |
0 |
| Defined Atom Stereocenter Count |
0 |
| Undefined Atom Stereocenter Count |
1 |
| Defined Bond Stereocenter Count |
0 |
| Undefined Bond Stereocenter Count |
0 |
| The total count of all stereochemical bonds |
0 |
| Covalently-Bonded Unit Count |
1 |
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