Basic Description

Synonyms	SB3-12 \| DTXCID8029078 \| dodecyldimethyl(3-sulfopropyl)ammonium hydroxide \| NCGC00260353-01 \| SY052089 \| n-dodecyl-n,n-dimethyl-3-ammonio-1-propanesulphonate \| N-DODECYL-N,N-DIMETHYL-3-AMMONIUM-1-PROPANESULFONATE \| naftidrofuryl hydrogen oxalate \| J-00857
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	Synthetic zwitterionic detergent, which unlike other amphoteric surfactants, retains its zwitterionic character over a broad pH range. This property is attributed to the presence of both a strongly basic quaternary ammonium ion and an acidic sulfonate ion
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate is a zwitterionic surfactant. N-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate has been used in a study to assess protein structural change in a mixed system of ionic and zwitterionic surfactants. It has also been used in a study to investigate the interaction between ionic liquid and zwitterionic surfactant.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - Class Organonitrogen compounds
    - Subclass Quaternary ammonium salts

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
Class	Organonitrogen compounds
Subclass	Quaternary ammonium salts
Intermediate Tree Nodes	Not available
Direct Parent	Tetraalkylammonium salts
Alternative Parents	Organosulfur compounds Organopnictogen compounds Organic zwitterions Organic salts Organic oxides Hydrocarbon derivatives Amines
Molecular Framework	Aliphatic acyclic compounds
Substituents	Tetraalkylammonium salt - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organic zwitterion - Organosulfur compound - Amine - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as tetraalkylammonium salts. These are organonitrogen compounds containing a quaternary ammonium substituted with four alkyl chains.
External Descriptors	a small molecule
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-[dodecyl(dimethyl)azaniumyl]propane-1-sulfonate
INCHI	InChI=1S/C17H37NO3S/c1-4-5-6-7-8-9-10-11-12-13-15-18(2,3)16-14-17-22(19,20)21/h4-17H2,1-3H3
InChIKey	IZWSFJTYBVKZNK-UHFFFAOYSA-N
Smiles	CCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
Isomeric SMILES	CCCCCCCCCCCC[N+](C)(C)CCCS(=O)(=O)[O-]
WGK Germany	2
PubChem CID	84703
UN Number	3261
Molecular Weight	335.55
Beilstein	4145308
Reaxy-Rn	4145308

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

22 results found

Lot Number	Certificate Type	Date	Item
L2406702	Certificate of Analysis	Nov 20, 2024	S105512
L2406683	Certificate of Analysis	Nov 20, 2024	S105512
L2406682	Certificate of Analysis	Nov 20, 2024	S105512
L2406684	Certificate of Analysis	Nov 20, 2024	S105512
J2424729	Certificate of Analysis	Sep 26, 2024	S105512
J2424731	Certificate of Analysis	Sep 26, 2024	S105512
J2424732	Certificate of Analysis	Sep 26, 2024	S105512
H2430552	Certificate of Analysis	Aug 02, 2024	S105512
H2430539	Certificate of Analysis	Aug 02, 2024	S105512
H2430553	Certificate of Analysis	Aug 02, 2024	S105512
H2318708	Certificate of Analysis	Aug 03, 2023	S105512
H2318709	Certificate of Analysis	Aug 03, 2023	S105512
A2429399	Certificate of Analysis	Aug 03, 2023	S105512
H2318710	Certificate of Analysis	Aug 03, 2023	S105512
E1818140	Certificate of Analysis	Apr 02, 2022	S105512
D1810210	Certificate of Analysis	Feb 21, 2022	S105512
B2223518	Certificate of Analysis	Dec 17, 2021	S105512
B2223524	Certificate of Analysis	Dec 17, 2021	S105512
B2223525	Certificate of Analysis	Dec 17, 2021	S105512
B2223450	Certificate of Analysis	Dec 17, 2021	S105512
B2324025	Certificate of Analysis	Dec 17, 2021	S105512
B2223528	Certificate of Analysis	Dec 17, 2021	S105512

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Chemical and Physical Properties

Solubility	Chloroform (Slightly), Methanol (Slightly)
Sensitivity	Moisture sensitive
Flash Point(°F)	110 °C
Flash Point(°C)	110°C
Melt Point(°C)	244°C(lit.)
Molecular Weight	335.500 g/mol
XLogP3	5.000
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	14
Exact Mass	335.249 Da
Monoisotopic Mass	335.249 Da
Topological Polar Surface Area	65.600 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	334.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Chenxiao Chu, Yaxin Deng, Hongbing Liu, Mingli Wei, Xiaohong Xu, Jingxin Gou, Haibing He, Tian Yin, Yu Zhang, Xing Tang. (2023) In situ rearranged multifunctional lipid nanoparticles via synergistic potentiation for oral insulin delivery. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 636 (122811).
2. Zhenwei Zhang, Junkai Zhang, Yixing Zhao, Yanli Wan, Sen Li, Yingwen Tang, Tao Li, Tingfang Tian, Li Wang. (2023) Reviving aged CsPbBr3 quantum dots by triallylamine etching. APPLIED SURFACE SCIENCE, 612 (155775).
3. Shuhuai Xia, Yujun Jiang, Xia Guo, Yaqiong Wang, Wenlin Xu. (2022) Effects of p-sulfonatocalixarene and p-sulfonatocalixarene/sulfobetaine surfactant complex on the activities of bromelain and polyphenol oxidase. JOURNAL OF MOLECULAR LIQUIDS, 367 (120398).
4. Zhijun Guo, Guangyue Bai, Xize Zhan, Kelei Zhuo, Jianji Wang, Yujie Wang. (2022) Supramolecular Vector/Drug Coassemblies of Polyglycerol Dendrons and Rutin Enhance the pH Response. LANGMUIR, 38 (11): (3392–3402).
5. Yanqing Zu, Jun Xi, Lu Li, Jinfei Dai, Shuangpeng Wang, Feng Yun, Bo Jiao, Hua Dong, Xun Hou, Zhaoxin Wu. (2020) High-Brightness and Color-Tunable FAPbBr3 Perovskite Nanocrystals 2.0 Enable Ultrapure Green Luminescence for Achieving Recommendation 2020 Displays. ACS Applied Materials & Interfaces, 12 (2): (2835–2841).
6. Liang Jin-Jin, Li Yun-Hui, Liu Fei, Li Hong-Ye, Liu Jie-Sheng, Yang Wei-Dong. (2015) Experimental removal of Alexandrium tamarense cells using sulfobetaines and their modified clays. JOURNAL OF APPLIED PHYCOLOGY, 27 (6): (2313-2319).
7. Shaoying Dai, Tengda Wang, Jie Cui, Junfeng Xiang, Qing Shao, Yuchun Han, Yilin Wang. (2025) Enhancing osmotic stress tolerance of cell mimetics by modulating lipid bilayer. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 678 (152).

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SKU	Size	Availability	Price
S105512-1g	1g	3	$10.90
S105512-5g	5g	3	$38.90
S105512-10g	10g	2	$70.90
S105512-25g	25g	3	$95.90
S105512-100g	100g	2	$336.90
S105512-250g	250g	2	$542.90

Sulfobetaine 12 - 98%, high purity , CAS No.14933-08-5