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Sulfathiazole sodium salt - ≥99%, high purity , CAS No.144-74-1

COA

Grade & Purity:

≥99%

Cas Number: 144-74-1
Molecular Weight: 277.3
EC Number: 205-638-5
PubChem CID: 12285822
PubChem SID: 504767036

In stock

Item Number

S346978

Grouped product items
SKU	Size	Availability	Price
S346978-5g	5g	2	$9.90
S346978-25g	25g	2	$15.90
S346978-100g	100g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$47.90

a competitive inhibitor of bacterial para-aminobenzoic acid (PABA)

View related series

Anti-infection (2803) Antibiotic (1629) Bacterial (3013)

Basic Description

Synonyms	BCP13309 \| s5963 \| Soluthiazomide \| Sodium sulphathiazole \| AKOS032953796 \| s12091 \| Sodium 2-sulfanilamidothiazole \| EINECS 205-638-5 \| SR-01000883699-1 \| Sulfathiazole sodium \| 4-Amino-N-(2-thiazolyl)benzenesulfonamide sodium salt \| sodium [(4-aminophen
Specifications & Purity	≥99%
Biochemical and Physiological Mechanisms	Sulfathiazole is a sulfonamide that blocks dihydrofolic acid production by inhibiting dihydropropionic acid synthase. Sulfathiazole is the Competitive inhibition of bacterial 4-Aminobenzoic Acid acid (PABA) , which is necessary for the bacteria to synthes
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Sulfathiazole sodium salt is a short-acting sulfa drug. It was a common oral and topical antibiotic until less toxic alternatives were discovered. It is no longer used in humans. Sulfathiazole is added to the diet of laboratory animals to inhibit folate formation by gut bacteria. This ensures that the animal′s only source of available folate is from their diet. Sulfathiazole is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfathiazole is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Benzenesulfonamides

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Benzenesulfonamides
Intermediate Tree Nodes	Not available
Direct Parent	Benzenesulfonamides
Alternative Parents	Benzenesulfonyl compounds Aniline and substituted anilines Thiazoles Sulfonyls Organosulfonic acids and derivatives Heteroaromatic compounds Azacyclic compounds Primary amines Organopnictogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Benzenesulfonamide - Benzenesulfonyl group - Aniline or substituted anilines - Azole - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Heteroaromatic compound - Thiazole - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Amine - Organic salt - Organic zwitterion - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Organosulfur compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504767036
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504767036
IUPAC Name	sodium;(4-aminophenyl)sulfonyl-(1,3-thiazol-2-yl)azanide
INCHI	InChI=1S/C9H8N3O2S2.Na/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9;/h1-6H,10H2;/q-1;+1
InChIKey	GWIJGCIVKLITQK-UHFFFAOYSA-N
Smiles	C1=CC(=CC=C1N)S(=O)(=O)[N-]C2=NC=CS2.[Na+]
Isomeric SMILES	C1=CC(=CC=C1N)S(=O)(=O)[N-]C2=NC=CS2.[Na+]
PubChem CID	12285822
Molecular Weight	277.3

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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3 results found

Lot Number	Certificate Type	Date	Item
L2220356	Certificate of Analysis	Dec 06, 2022	S346978
L2220357	Certificate of Analysis	Dec 06, 2022	S346978
L2220358	Certificate of Analysis	Dec 06, 2022	S346978

Chemical and Physical Properties

Sensitivity	Moisture sensitive
Molecular Weight	277.300 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	3
Exact Mass	276.996 Da
Monoisotopic Mass	276.996 Da
Topological Polar Surface Area	111.000 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	326.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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