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Sulfadiazine sodium salt - 10mM in DMSO, high purity , CAS No.547-32-0, Bacterial dihydropteroate synthase inhibitor

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
S424665
Grouped product items
SKU Size
Availability
Price Qty
S424665-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$69.90

Basic Description

Synonyms Sodium sulfadiazine | SULFADIAZINE SODIUM | 547-32-0 | Sulfadiazin-natrium | Soludiazine | Suthogen | Sodium sulfapyrimidine | Sulfadiazina sodica | Soluble sulfadiazine | Sulfadiazine (sodium) | Monosodium 2-sulfanilamidopyrimidine | 2-Sulfanilamidopyrimidine sodium salt | EINE
Specifications & Purity 10mM in DMSO
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type INHIBITOR
Mechanism of action Bacterial dihydropteroate synthase inhibitor
Product Description

Application

Sulfadiazine may be used as an internal standard for the determination of sulfapyridine in biological samples using high-performance liquid chromatography technique.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Benzenoids
Class Benzene and substituted derivatives
Subclass Benzenesulfonamides
Intermediate Tree Nodes Not available
Direct Parent Benzenesulfonamides
Alternative Parents Benzenesulfonyl compounds  Aniline and substituted anilines  Pyrimidines and pyrimidine derivatives  Sulfonyls  Organosulfonic acids and derivatives  Heteroaromatic compounds  Azacyclic compounds  Primary amines  Organopnictogen compounds  Organic zwitterions  Organic sodium salts  Organic oxides  Hydrocarbon derivatives  
Molecular Framework Aromatic heteromonocyclic compounds
Substituents Benzenesulfonamide - Benzenesulfonyl group - Aniline or substituted anilines - Pyrimidine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Sulfonyl - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Organic alkali metal salt - Amine - Organic salt - Organic zwitterion - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary amine - Organosulfur compound - Organonitrogen compound - Organic sodium salt - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as benzenesulfonamides. These are organic compounds containing a sulfonamide group that is S-linked to a benzene ring.
External Descriptors Not available

Names and Identifiers

IUPAC Name sodium;(4-aminophenyl)sulfonyl-pyrimidin-2-ylazanide
INCHI InChI=1S/C10H9N4O2S.Na/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10;/h1-7H,11H2;/q-1;+1
InChIKey JLDCNMJPBBKAHH-UHFFFAOYSA-N
Smiles C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+]
Isomeric SMILES C1=CN=C(N=C1)[N-]S(=O)(=O)C2=CC=C(C=C2)N.[Na+]
WGK Germany 3
RTECS WP2000000
PubChem CID 15899898
Molecular Weight 272.26
Beilstein 4068213

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Molecular Weight 272.260 g/mol
XLogP3
Hydrogen Bond Donor Count 1
Hydrogen Bond Acceptor Count 6
Rotatable Bond Count 3
Exact Mass 272.034 Da
Monoisotopic Mass 272.034 Da
Topological Polar Surface Area 95.300 Ų
Heavy Atom Count 18
Formal Charge 0
Complexity 332.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Citations of This Product

1. Huang Jialu, Zhang Shuchi, Tan Mengyu, Shen Jie, Zhao Haiyan, Wu Donglei.  (2023)  Occurrence, removal, and risk assessment of emerging contaminants in aquatic products processing sewage treatment plants.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,    (1-13). 
2. Wenming Yang, Mingyue Kuai, Changchun Wu, Wenqi Yang, Lingling Cao, Yi Zhang, Ting Chen, Yunfei Cao, Baozhi Wang, Wanzhen Xu.  (2023)  Dual-emission ratiometric fluorescence sensors based on silica, molecularly imprinted polymers and carbon quantum dots for high-sensitivity and high-selectivity detection of sulfadiazine.  POLYMER INTERNATIONAL,     
3. Jingyang Luo, Zhicheng Wei, Xiaoshi Cheng, Xinyi Liu, Feng Wang, Wenxuan Huang, Shiyu Fang, Junfeng Wu, Yang Wu, Jianchao Liu, Le Zhang.  (2023)  Surfactant and antibiotic co-occurrence reshaped the acidogenic process for volatile fatty acids production during sludge anaerobic fermentation.  SCIENCE OF THE TOTAL ENVIRONMENT,  905  (167064). 
4. Jing Dai, Ziqian Wang, Aoxue Zhu, Yuefei Ji, Zhe Kong, Tianming Cai, Dahu Ding.  (2023)  Elimination of sulfadiazine and its metabolite from hydrolyzed urine by biochar activated periodate process: Lower environmental risk compared with CoFe2O4/peroxymonosulfate process.  CHEMICAL ENGINEERING JOURNAL,  472  (145080). 
5. Weiping Chen, Bingzheng Wang, Yaqing Wang, Ji Li.  (2023)  Understanding the cometabolic degradation of sulfadiazine by an enriched ammonia oxidizing bacteria culture from both extracellular and intracellular perspectives.  CHEMOSPHERE,  336  (139244). 
6. Xuan Zhou, Jiaxin Li, Yuda Hu, Yaohui Wu, Yonghong Wang, Ge Ning.  (2023)  A novel colorimetric assay for sensitive detection of kanamycin based on the aptamer-regulated peroxidase-mimicking activity of Co3O4 nanoparticles.  Analytical Methods,     
7. Yuchen Wang, Mengqin Li, Liangyu Zhu, Yanmei Wang.  (2023)  On-line preconcentration and determination of sulfadiazine in food samples using surface molecularly imprinted polymer coating by capillary electrophoresis.  JOURNAL OF CHROMATOGRAPHY A,  1696  (463965). 
8. Yuan Liu, Zhen Tao, Hailong Lu, Siyi Li, Chao Hu, Zhongyang Li.  (2023)  Electrochemical properties of roots determine antibiotic adsorption on roots..  Frontiers in Plant Science,  14  (930632-930632). 
9. Jingxuan Yang, Dongxu Qu, Jue Wang, Yangtao Wu, Lingjun Bu, Yuanxi Huang, Shiqing Zhou.  (2023)  UV-induced degradation of contaminants of emerging concern in the presence of monobromoamine: Role of N-Br bond and degradation mechanisms.  Journal of Environmental Chemical Engineering,  11  (109646). 
10. Feng Wang, Le Zhang, Yuting Luo, Yi Li, Xiaoshi Cheng, Jiashun Cao, Junfeng Wu, Haining Huang, Jingyang Luo, Yinglong Su.  (2023)  Surfactant aggravated the antibiotic's stress on antibiotic resistance genes proliferation by altering antibiotic solubilization and microbial traits in sludge anaerobic fermentation.  SCIENCE OF THE TOTAL ENVIRONMENT,  873  (162440). 
11. Chao Liu, Zhenxiang Chen, Ruiqin Kang, Jing Wang, Qingwei Lu, Tao Wang, Dayong Tian, Ying Xu, Zhan Wang, Huiping Ding.  (2023)  N-Rich Algal Sludge Biochar for Peroxymonosulfate Activation toward Sulfadiazine Removal.  Coatings,  13  (2): (431). 
12. Chen-Ting Zhu, Kai-Yuan Huang, Qing-Lin Zhou, Xiang-Ping Zhang, Gang-Wei Wu, Hua-Ping Peng, Hao-Hua Deng, Wei Chen, Hamada A.A. Noreldeen.  (2023)  Multi-excitation wavelength of gold nanocluster-based fluorescence sensor array for sulfonamides discrimination.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  288  (122138). 
13. Yan Yan, Xiangjuan Ma, Yijing Xia, Huajun Feng, Shengjue Liu, Cong He, Yangcheng Ding.  (2023)  Mechanism of highly efficient electrochemical degradation of antibiotic sulfadiazine using a layer-by-layer GNPs/PbO2 electrode.  ENVIRONMENTAL RESEARCH,  217  (114778). 
14. Yanzhuo Zhang, Jing Zhao.  (2022)  Comparison of different S-doped biochar materials to activate peroxymonosulfate for efficient degradation of antibiotics.  CHEMOSPHERE,  308  (136442). 
15. Yan Wang, Tao Gan, Jingyu Xiu, Ganghua Liu, Haiming Zou.  (2022)  Degradation of sulfadiazine in aqueous media by peroxymonosulfate activated with biochar-supported ZnFe2O4 in combination with visible light in an internal loop-lift reactor.  RSC Advances,  12  (37): (24088-24100). 
16. Lulan Yang, Xingyue Chen, Xu Wen, Jiaming Tang, Xiaoling Zheng, Jiaqi Li, Lingling Chen, Shuang Jiang, Tao Le.  (2022)  A label-free dual-modal aptasensor for colorimetric and fluorescent detection of sulfadiazine.  Journal of Materials Chemistry B,  10  (32): (6187-6193). 
17. Yuanxi Huang, Lingjun Bu, Yangtao Wu, Shumin Zhu, Shiqing Zhou, Zhou Shi, Dionysios D. Dionysiou.  (2022)  Degradation of contaminants of emerging concern in UV/Sodium percarbonate Process: Kinetic understanding of carbonate radical and energy consumption evaluation.  CHEMICAL ENGINEERING JOURNAL,  442  (135995). 
18. Zeng Xue-Yu, Wang Yu, Li Rong-Xin, Cao Hai-Lei, Li Ya-Feng, Lü Jian.  (2022)  Impacts of temperatures and phosphoric-acid modification to the physicochemical properties of biochar for excellent sulfadiazine adsorption.  Biochar,  (1): (1-14). 
19. Yanzhuo Zhang, Shengxu Liang, Rui He, Jing Zhao, Jinghua Lv, Wei Kang, Jian Zhang.  (2022)  Enhanced adsorption and degradation of antibiotics by doping corncob biochar/PMS with heteroatoms at different preparation temperatures: Mechanism, pathway, and relative contribution of reactive oxygen species.  Journal of Water Process Engineering,  46  (102626). 
20. Xu Qiao, Yuhan Xia, Xuhan Su, Bingkun Wang, Guang Chen, Huan Chen.  (2022)  Preparation of biomass carbon material based on fulvic acid and its application in dye and antibiotic treatments.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,  638  (128302). 
21. Yang Zong, Hua Zhang, Yufei Shao, Wenjie Ji, Yunqiao Zeng, Longqian Xu, Deli Wu.  (2022)  Surface-mediated periodate activation by nano zero-valent iron for the enhanced abatement of organic contaminants.  JOURNAL OF HAZARDOUS MATERIALS,  423  (126991). 
22. Fuwei Sun, Tianhu Chen, Haibo Liu, Xuehua Zou, Peixun Zhai, Ziyang Chu, Daobing Shu, Hanlin Wang, Dong Chen.  (2021)  The pH-dependent degradation of sulfadiazine using natural siderite activating PDS: The role of singlet oxygen.  SCIENCE OF THE TOTAL ENVIRONMENT,  784  (147117). 
23. Fuwei Sun, Tianhu Chen, Xuehua Zou, Haibo Liu, Ziyang Chu, Daobing Shu, Hanlin Wang, Fangju Huang, Dong Chen.  (2021)  A quantitative analysis of hydroxyl radical generation as H2O2 encounters siderite: Kinetics and effect of parameters.  APPLIED GEOCHEMISTRY,  126  (104893). 
24. Xinxiang Geng, Siying Lv, Jing Yang, Shihai Cui, Zehua Zhao.  (2021)  Carboxyl-functionalized biochar derived from walnut shells with enhanced aqueous adsorption of sulfonamide antibiotics.  JOURNAL OF ENVIRONMENTAL MANAGEMENT,  280  (111749). 
25. Xianglei He, Jialiang Li, Qingmei Meng, Ziyu Guo, Hao Zhang, Yurong Liu.  (2021)  Enhanced adsorption capacity of sulfadiazine on tea waste biochar from aqueous solutions by the two-step sintering method without corrosive activator.  Journal of Environmental Chemical Engineering,  (104898). 
26. K.M. Wang, J. Shu, S.J. Wang, T.Y. Hong, X.P. Xu, H.Y. Wang.  (2020)  Efficient electrochemical generation of ferrate(VI) by iron coil anode imposed with square alternating current and treatment of antibiotics.  JOURNAL OF HAZARDOUS MATERIALS,  384  (121458). 
27. Fan Zhang, Nan Ye, Se Wang, Yue Meng, Hao Fang, Zhuang Wang, De-Gao Wang.  (2019)  Dissolved Organic Matter Modulates Algal Oxidative Stress and Membrane System Responses to Binary Mixtures of Nano-Metal-Oxides (nCeO2, nMgO and nFe3O4) and Sulfadiazine.  Nanomaterials,  (5): (712). 
28. Jing Xie, Xu Duan, Leiyu Feng, Yuanyuan Yan, Feng Wang, Haiqing Dong, Renyong Jia, Qi Zhou.  (2019)  Influence of sulfadiazine on anaerobic fermentation of waste activated sludge for volatile fatty acids production: Focusing on microbial responses.  CHEMOSPHERE,  219  (305). 
29. Guanglan Di, Zhiliang Zhu, Qinghui Huang, Hua Zhang, Jianyao Zhu, Yanling Qiu, Daqiang Yin, Jianfu Zhao.  (2019)  Targeted modulation of g-C3N4 photocatalytic performance for pharmaceutical pollutants in water using ZnFe-LDH derived mixed metal oxides: Structure-activity and mechanism.  SCIENCE OF THE TOTAL ENVIRONMENT,  650  (1112). 
30. Tuqiao Zhang, Feilong Dong, Feng Luo, Cong Li.  (2018)  Degradation of sulfonamides and formation of trihalomethanes by chlorination after pre-oxidation with Fe(VI).  Journal of Environmental Sciences,  73  (89). 
31. Xiuping He, Liju Tan, Wei Wu, Jiangtao Wang.  (2016)  Determination of sulfadiazine in eggs using molecularly imprinted solid-phase extraction coupled with high-performance liquid chromatography.  JOURNAL OF SEPARATION SCIENCE,  39  (11): (2204-2212). 
32. Pengfei Ma, Zhiping Zhou, Wenming Yang, Bingqing Tang, Hong Liu, Wanzhen Xu, Weihong Huang.  (2014)  Preparation and application of sulfadiazine surface molecularly imprinted polymers with temperature-responsive properties.  JOURNAL OF APPLIED POLYMER SCIENCE,  132  (15):  
33. Shao-Peng Rong, Ya-Bing Sun, Ze-Hua Zhao.  (2014)  Degradation of sulfadiazine antibiotics by water falling film dielectric barrier discharge.  CHINESE CHEMICAL LETTERS,  25  (187). 
34. Fang Yu, Chang Liu, Yuhong Guo, Yaling Yang.  (2013)  Ultrasound-assisted cloud point extraction for the determination of sulfonamides in honey samples by fluorescence spectrophotometry.  Analytical Methods,  (16): (3920-3926). 
35. Guohao Zhai, Yuxuan Ma, Huixian Liu, Hongtao Jia, Shanshan Wang, Shuai Liu.  (2024)  Adsorption of sulfadiazine from water by Pedicularis kansuensis derived biochar: Preparation and properties studies.  JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,     
36. Jiale Xu, Yuting Zhang, Shaoxin Zi, Xuanqi Zhang, Zhengtong Qian, Jin Liu.  (2025)  Aging-mediated selective adsorption of antibiotics by tire wear particles: Hydrophobic and electrostatic interactions effects.  JOURNAL OF CONTAMINANT HYDROLOGY,  269  (104482). 
37. Zhi Mei, Fang Wang, Yuhao Fu, Yu Liu, Syed A. Hashsham, Yu Wang, Jean Damascene Harindintwali, Qingyuan Dou, Marko Virta, Xin Jiang, Yu Deng, Tong Zhang, James M. Tiedje.  (2024)  Biofilm enhanced the mitigations of antibiotics and resistome in sulfadiazine and trimethoprim co-contaminated soils.  JOURNAL OF HAZARDOUS MATERIALS,  479  (135721). 
38. Zhang Xuxin, Li Yihao, Xia Shaojie, Yang Zhenyuan, Zhang Baiyun, Wang Yonghong.  (2024)  Chemiluminescence detection of kanamycin by DNA aptamer regulating peroxidase-like activity of Co3O4 nanoparticles.  ANALYTICAL SCIENCES,    (1-9). 
39. Zhang Zekun, Zhao Le, Yang Jie, Pang Jiayin, Lambers Hans, He Honghua.  (2024)  Effects of environmentally relevant concentrations of oxytetracycline and sulfadiazine on the bacterial communities, antibiotic resistance genes, and functional genes are different between maize rhizosphere and bulk soil.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,    (1-16). 
40. Yifei Leng, Ying Zhang, Xiong Chen, Ting He, Fengyi Chang, Zhu Li, Yu Huang, Jun Wang, Wen Xiong.  (2025)  Enhanced transformation of sulfadiazine by horseradish peroxidase activated persulfate progress: Characteristics, pathways, mechanisms, and ecotoxicities.  Journal of Environmental Chemical Engineering,  13  (116140). 
41. Tao Zhao, Minghao Xu, Xuerui Yang, Jean-Marc Chovelon, Lei Zhou.  (2025)  Exploring the reactivity of high-valent copper species with emerging contaminants using predictive QSAR modelling.  ENVIRONMENTAL TECHNOLOGY,     
42. Chen Yi, Jin Yue, Zhu Honglin, Zhang Haolan, Wei Luyu, Tang Yan, Wang Rui, Zhou Dayu, Gu Jinchuan.  (2025)  Novel MoS2/BaSO4/zeolite heterostructure composite for the enhanced visible-light photocatalytic degradation of sulfadiazine.  npj Clean Water,  (1): (1-14). 
43. Ye Huang, Haifei Kang, Yue Wang, Kun Liu, Wenying Wei, Honglian Dai.  (2024)  One Stone Three Birds: Silver Sulfadiazine Modulates the Stability and Dynamics of Hydrogels for Infected Wound Healing.  Advanced Healthcare Materials,    (2400242). 
44. Xiaoshi Cheng, Le Zhang, Zhicheng Wei, Xinyi Liu, Xiong Shi, Xuran Liu, Jiashun Cao, Qian Feng, Fang Fang, Jingyang Luo.  (2025)  Overlooked roles of improved substrates functions in remodeling microbial community and driving metabolic traits during sludge fermentation triggered by surfactants and antibiotics co-existence.  JOURNAL OF HAZARDOUS MATERIALS,  482  (136617). 
45. Xiaoyan Bai, Wei Wang, Jian Sun, Yulei Xie.  (2024)  Preparation of printing and dyeing sludge biochar/macromolecule polymer microsphere as a non-sacrificial persulfate activator with excellent reusability and reduced heavy metals leaching.  CHEMICAL ENGINEERING JOURNAL,  500  (156726). 
46. Shen Zhang, Shuhua Li, Dong Li, Jizhong Wu, Tianhui Jiao, Jie Wei, Xiaomei Chen, Qingmin Chen, Quansheng Chen.  (2024)  Sulfadiazine detection in aquatic products using upconversion nanosensor based on photo-induced electron transfer with imidazole ligands and copper ions.  FOOD CHEMISTRY,  456  (139992). 

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