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STING inhibitor C-178 - 98%, high purity , CAS No.329198-87-0

COA

Grade & Purity:

≥98%

Cas Number: 329198-87-0
Molecular Weight: 322.27
PubChem CID: 2866412
PubChem SID: 504762238

In stock

Item Number

S413577

Grouped product items
SKU	Size	Availability	Price
S413577-10mg	10mg	3	$117.90
S413577-50mg	50mg	2	$375.90
S413577-250mg	250mg	2	$1,692.90
S413577-1g	1g	2	$6,091.90

STING Inhibitors

View related series

Immunology/Inflammation (1929) STING (52)

Basic Description

Synonyms	C 178 \| C178 \| N-(Dibenzo[b,d]furan-3-yl)-5-nitrofuran-2-carboxamide \| N-Dibenzofuran-3-yl-5-nitrofuran-2-carboxamide \| N-3-Dibenzofuranyl-5-nitro-2-furancarboxamide \| 2-Furancarboxamide,N-3-dibenzofuranyl-5-nitro-
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	C-178 is a covalent inhibitor of STING,covalently bind to Cys91.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information STING inhibitor C-178 C-178 is a covalent inhibitor of STING ,covalently bind to Cys91. Targets STING

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Benzofurans
    - Subclass Dibenzofurans

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Benzofurans
Subclass	Dibenzofurans
Intermediate Tree Nodes	Not available
Direct Parent	Dibenzofurans
Alternative Parents	2-heteroaryl carboxamides Furoic acid and derivatives Nitroaromatic compounds Nitrofurans Benzenoids Heteroaromatic compounds Secondary carboxylic acid amides Propargyl-type 1,3-dipolar organic compounds Oxacyclic compounds Organic oxoazanium compounds Organic oxides Hydrocarbon derivatives Organic zwitterions Organonitrogen compounds Organooxygen compounds Organopnictogen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Dibenzofuran - 2-heteroaryl carboxamide - Furoic acid or derivatives - Nitroaromatic compound - 2-nitrofuran - Benzenoid - Furan - Heteroaromatic compound - Carboxamide group - C-nitro compound - Secondary carboxylic acid amide - Organic nitro compound - Carboxylic acid derivative - Organic oxoazanium - Oxacycle - Organic 1,3-dipolar compound - Allyl-type 1,3-dipolar organic compound - Propargyl-type 1,3-dipolar organic compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organooxygen compound - Organic zwitterion - Organic oxygen compound - Organopnictogen compound - Organic oxide - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as dibenzofurans. These are compounds containing a dibenzofuran moiety, which consists of two benzene rings fused to a central furan ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504762238
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504762238
IUPAC Name	N-dibenzofuran-3-yl-5-nitrofuran-2-carboxamide
INCHI	InChI=1S/C17H10N2O5/c20-17(14-7-8-16(24-14)19(21)22)18-10-5-6-12-11-3-1-2-4-13(11)23-15(12)9-10/h1-9H,(H,18,20)
InChIKey	URUVDCCYSJEGQQ-UHFFFAOYSA-N
Smiles	C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)NC(=O)C4=CC=C(O4)[N+](=O)[O-]
Isomeric SMILES	C1=CC=C2C(=C1)C3=C(O2)C=C(C=C3)NC(=O)C4=CC=C(O4)[N+](=O)[O-]
PubChem CID	2866412
Molecular Weight	322.27

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number	Certificate Type	Date	Item
G2220138	Certificate of Analysis	May 09, 2025	S413577
G2220090	Certificate of Analysis	May 09, 2025	S413577
G2220089	Certificate of Analysis	May 09, 2025	S413577
G2220087	Certificate of Analysis	May 09, 2025	S413577

Chemical and Physical Properties

Solubility	Solubility (25°C) In vitro DMSO: 32 mg/mL (99.29 mM); Water: Insoluble; Ethanol: Insoluble;
Molecular Weight	322.270 g/mol
XLogP3	4.100
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	322.059 Da
Monoisotopic Mass	322.059 Da
Topological Polar Surface Area	101.000 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	508.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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