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Stafib-2 - 10mM in DMSO, high purity , CAS No.2097938-74-2(DMSO)

COA

Grade & Purity:

10mM in DMSO

Cas Number: 2097938-74-2(DMSO)
Molecular Weight: 644.46

In stock

Item Number

S655347

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SKU	Size	Availability	Price	Qty
S655347-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,163.90

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Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b , with an IC 50 of 82 nM and 1.7 μM for STAT5b and STAT5a , respectively. Stafib-2 exhibits poor cell permeability.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b , with an IC 50 of 82 nM and 1.7 μM for STAT5b and STAT5a , respectively. Stafib-2 exhibits poor cell permeability In Vitro Stafib-2 has an extremely high affinity for STAT5b (K i =8.8 nM). Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 82 nM (STAT5b)

Names and Identifiers

Smiles	C1=CC=C(C=C1)OC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)OCC(=O)NCC4=CC(=C(C=C4)OP(=O)(O)O)OP(=O)(O)O
Molecular Weight	644.46

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