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ST 271 - 10mM in DMSO, high purity , CAS No.106392-48-7

COA

Grade & Purity:

10mM in DMSO

Cas Number: 106392-48-7
Molecular Weight: 272.34
PubChem CID: 6439072

In stock

Item Number

S420501

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SKU	Size	Availability	Price	Qty
S420501-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$241.90

Phospholipase

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Compound libraries (12325) Lipid metabolism (1912)

Basic Description

Synonyms	106392-48-7 \| ST271 \| ST 271 \| ST-271 \| (E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide \| 2-Propenamide, 2-cyano-3-(4-hydroxy-3,5-bis(1-methylethyl)phenyl)- \| CHEMBL504173 \| 2-cyano-3-(4-hydroxy-3,5-diisopropylphenyl)acrylamide \| BCP20728 \| EX-A5845 \| BDBM5
Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information ST 271 ST271 is a tyrphostin-like protein tyrosine kinase (PTK) inhibitor which inhibits phospholipase D (PLD) activity. Targets PLD

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Phenylpropanoids and polyketides
  - Class Cinnamic acids and derivatives
    - Subclass Hydroxycinnamic acids and derivatives

Kingdom	Organic compounds
Superclass	Phenylpropanoids and polyketides
Class	Cinnamic acids and derivatives
Subclass	Hydroxycinnamic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Coumaric acids and derivatives
Alternative Parents	Cinnamic acid amides Phenylpropanes Cumenes Phenols Primary carboxylic acid amides Nitriles Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic homomonocyclic compounds
Substituents	Cinnamic acid amide - Coumaric acid or derivatives - Cumene - Phenylpropane - Phenol - Monocyclic benzene moiety - Benzenoid - Carboxamide group - Primary carboxylic acid amide - Nitrile - Carbonitrile - Carboxylic acid derivative - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Cyanide - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as coumaric acids and derivatives. These are aromatic compounds containing Aromatic compounds containing a cinnamic acid moiety (or a derivative thereof) hydroxylated at the C2 (ortho-), C3 (meta-), or C4 (para-) carbon atom of the benzene ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Product Properties

ALogP	3.285
HBD Count	2
Rotatable Bond	4

Names and Identifiers

IUPAC Name	(E)-2-cyano-3-[4-hydroxy-3,5-di(propan-2-yl)phenyl]prop-2-enamide
INCHI	InChI=1S/C16H20N2O2/c1-9(2)13-6-11(5-12(8-17)16(18)20)7-14(10(3)4)15(13)19/h5-7,9-10,19H,1-4H3,(H2,18,20)/b12-5+
InChIKey	HMLQHJRJKQDTKW-LFYBBSHMSA-N
Smiles	CC(C)C1=CC(=CC(=C1O)C(C)C)C=C(C#N)C(=O)N
Isomeric SMILES	CC(C)C1=CC(=CC(=C1O)C(C)C)/C=C(\C#N)/C(=O)N
PubChem CID	6439072
Molecular Weight	272.34

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility	54
DMSO(mM) Max Solubility	198.281559814937
Water(mg / mL) Max Solubility	＜1
Molecular Weight	272.340 g/mol
XLogP3	3.000
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	272.152 Da
Monoisotopic Mass	272.152 Da
Topological Polar Surface Area	87.100 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	413.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

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