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GPCR/G Protein
Opioid Receptor
SR17018 - 98%, high purity , CAS No.2134602-45-0

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SR17018 - 98%, high purity , CAS No.2134602-45-0

COA

Grade & Purity:

≥98%

Cas Number: 2134602-45-0
Molecular Weight: 410.72
PubChem CID: 130431397

In stock

Item Number

S412194

Grouped product items
SKU	Size	Availability	Price
S412194-5mg	5mg	2	$59.90
S412194-10mg	10mg	2	$89.90
S412194-25mg	25mg	2	$199.90
S412194-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$329.90
S412194-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$539.90

View related series

Class A GPCR (4138) GPCR/G Protein (3172) Neuronal Signaling (3320) Opioid Receptor (113)

Basic Description

Synonyms	C74028 \| 5,6-dichloro-1-(1-(4-chlorobenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one \| AC-35518 \| EX-A1860 \| A16902 \| BCP29030 \| SR-17018; SR 17018 \| 2134602-45-0 \| CS-0040938 \| 2H-Benzimidazol-2-one, 5,6-dichloro-1-(1-((4-chlorophenyl)methyl)-4-piper
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	SR17018 is an agonist of mu-opioid-receptor (MOR) binding with GTPγS with EC50 of 97 nM.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Information SR17018 is an agonist of mu-opioid-receptor (MOR) binding with GTPγS with EC50 of 97 nM.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Piperidines
    - Subclass Benzylpiperidines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Piperidines
Subclass	Benzylpiperidines
Intermediate Tree Nodes	Not available
Direct Parent	N-benzylpiperidines
Alternative Parents	Benzimidazoles Phenylmethylamines Benzylamines Chlorobenzenes Aralkylamines N-substituted imidazoles Heteroaromatic compounds Trialkylamines Organic carbonic acids and derivatives Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organochlorides Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	N-benzylpiperidine - Benzimidazole - Phenylmethylamine - Benzylamine - Aralkylamine - Halobenzene - Chlorobenzene - Benzenoid - N-substituted imidazole - Monocyclic benzene moiety - Heteroaromatic compound - Imidazole - Azole - Tertiary aliphatic amine - Tertiary amine - Carbonic acid derivative - Azacycle - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as n-benzylpiperidines. These are heterocyclic Compounds containing a piperidine ring conjugated to a benzyl group through one nitrogen ring atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

OPRM1 Tclin Mu-type opioid receptor (2 Activities)

Discover Target: OPRM1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

OPRM1 Tclin Mu opioid receptor (19785 Activities)

Discover Target: OPRM1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

OPRD1 Tclin Delta opioid receptor (15096 Activities)

Discover Target: OPRD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	5,6-dichloro-3-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one
INCHI	InChI=1S/C19H18Cl3N3O/c20-13-3-1-12(2-4-13)11-24-7-5-14(6-8-24)25-18-10-16(22)15(21)9-17(18)23-19(25)26/h1-4,9-10,14H,5-8,11H2,(H,23,26)
InChIKey	LAGUDYUGRSQDKS-UHFFFAOYSA-N
Smiles	C1CN(CCC1N2C3=CC(=C(C=C3NC2=O)Cl)Cl)CC4=CC=C(C=C4)Cl
Isomeric SMILES	C1CN(CCC1N2C3=CC(=C(C=C3NC2=O)Cl)Cl)CC4=CC=C(C=C4)Cl
PubChem CID	130431397
Molecular Weight	410.72

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot Number	Certificate Type	Date	Item
L2320147	Certificate of Analysis	Nov 30, 2023	S412194
L2320148	Certificate of Analysis	Nov 30, 2023	S412194
L2320149	Certificate of Analysis	Nov 30, 2023	S412194
L2320150	Certificate of Analysis	Nov 30, 2023	S412194
L2320151	Certificate of Analysis	Nov 30, 2023	S412194

Chemical and Physical Properties

Molecular Weight	410.700 g/mol
XLogP3	4.700
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	409.052 Da
Monoisotopic Mass	409.052 Da
Topological Polar Surface Area	35.600 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	506.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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