Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
S658950-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$250.90
|
|
|
S658950-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$420.90
|
|
|
S658950-25mg
|
25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$890.90
|
|
|
S658950-50mg
|
50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,500.90
|
|
| Specifications & Purity | ≥99% |
|---|---|
| Storage Temp | Store at 2-8°C,Desiccated |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM. Appearance:Solid In Vitro:SPOP-IN-6b dihydrochloride shows IC 50 s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN In Vivo:SPOP-IN-6b (40-80mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) dihydrochloride can slow down the growth of tumour by suppressing SPOP. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM. |
| Smiles | O=C(C(C(N1CCC2=CC=CC=C2)=N)=CC3=C1N=C(C(C)=CC=C4)N4C3=O)NCCCN5CCOCC5.[H]Cl.[H]Cl |
|---|---|
| Molecular Weight | 573.51 |
| Solubility | DMSO : 41.67 mg/mL (72.66 mM; ultrasonic and warming and heat to 60°C) |
|---|