This is a demo store. No orders will be fulfilled.

Spiramycin - 10mM in DMSO, high purity , CAS No.8025-81-8

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
S426067
Grouped product items
SKU Size
Availability
Price Qty
S426067-1ml
1ml
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$172.90

Macrolide antibiotic

Basic Description

Synonyms spiramycin | 8025-81-8 | Formacidine | Prestwick_121 | ST075006 | Prestwick2_000745 | Prestwick3_000745 | BPBio1_000804 | SCHEMBL5032756 | AKOS015896378 | SR-01000872632 | SR-01000872632-1 | Spiramycin, European Pharmacopoeia (EP) Reference Standard | Spiramycin from Streptomyces
Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Macrolide antibiotic. Inhibits bacterial translocation of protein synthesis.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic oxygen compounds
Class Organooxygen compounds
Subclass Carbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Aminosaccharides
Direct Parent Aminoglycosides
Alternative Parents Macrolides and analogues  Disaccharides  O-glycosyl compounds  Oxanes  Alpha-hydrogen aldehydes  Tertiary alcohols  1,2-aminoalcohols  Trialkylamines  Amino acids and derivatives  Carboxylic acid esters  Secondary alcohols  Lactones  Acetals  Dialkyl ethers  Oxacyclic compounds  Monocarboxylic acids and derivatives  Hydrocarbon derivatives  Organopnictogen compounds  Organic oxides  
Molecular Framework Aliphatic heteromonocyclic compounds
Substituents Aminoglycoside core - Macrolide - Disaccharide - Glycosyl compound - O-glycosyl compound - Oxane - Alpha-hydrogen aldehyde - Tertiary alcohol - 1,2-aminoalcohol - Amino acid or derivatives - Carboxylic acid ester - Lactone - Tertiary aliphatic amine - Secondary alcohol - Tertiary amine - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Oxacycle - Acetal - Carboxylic acid derivative - Dialkyl ether - Ether - Carbonyl group - Organopnictogen compound - Organonitrogen compound - Amine - Alcohol - Organic nitrogen compound - Organic oxide - Hydrocarbon derivative - Aldehyde - Aliphatic heteromonocyclic compound
Description This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
External Descriptors Not available

Names and Identifiers

IUPAC Name 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[5-(4,5-dihydroxy-4,6-dimethyloxan-2-yl)oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
INCHI InChI=1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26?,27?,28?,29+,30?,31-,32+,34?,35?,36?,37?,38?,39+,40+,41?,42?,43?/m1/s1
InChIKey ACTOXUHEUCPTEW-JMRHEKERSA-N
Smiles CC1CC=CC=CC(C(CC(C(C(C(CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C
Isomeric SMILES C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)OC4CCC(C(O4)C)N(C)C
WGK Germany 1
RTECS WG9400000
PubChem CID 6419898
Molecular Weight 843.06

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Specific Rotation[α] 81 ° (C=2, 10% AcOH)
Melt Point(°C) 134-137°C
Molecular Weight 843.100 g/mol
XLogP3 2.100
Hydrogen Bond Donor Count 4
Hydrogen Bond Acceptor Count 16
Rotatable Bond Count 11
Exact Mass 842.514 Da
Monoisotopic Mass 842.514 Da
Topological Polar Surface Area 195.000 Ų
Heavy Atom Count 59
Formal Charge 0
Complexity 1370.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 7
Undefined Atom Stereocenter Count 12
Defined Bond Stereocenter Count 2
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 2
Covalently-Bonded Unit Count 1

Citations of This Product

1. Yan Weifeng, Cui Zhe, Li Wenxin, An Xin, Cheng Xu, Wang Sihong, Jin Chunmei.  (2023)  Anti- Toxoplasma gondii Properties of Ginseng polysaccharides and saponins.  PHARMAZIE,     
2. Qi He, Dandan Wang, Jing Shao, Yi Li, Ming Cheng, Lihui Dong, Yunhui Li, Jianwei Zhu, Hongji Li.  (2023)  Multicomponent SERS imprinted bio-membrane based on eggshell membrane for selective detection of spiramycin in water.  JOURNAL OF MOLECULAR STRUCTURE,  1289  (135883). 
3. Hongji Li, Junfu Wang, Xiyue Wang, Haochen Yu, Linjing Ji, Tianyu Zhou, Chunbo Liu, Guangbo Che, Dandan Wang.  (2022)  A high-performance SERS imprinted membrane based on Ag/CNTs for selective detection of spiramycin.  SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,  281  (121587). 
4. Lin Wang, Tingting Yan, Ruijie Tang, Qian Ping, Yongmei Li, Jie Wang.  (2021)  Motivation of reactive oxidation species in peracetic acid by adding nanoscale zero-valent iron to synergic removal of spiramycin under ultraviolet irradiation: Mechanism and N-nitrosodimethylamine formation potential assessment.  WATER RESEARCH,  205  (117684). 
5. Guoqi Sui, Xiuyun Yang, Hongji Li, Yunhui Li, Leijiao Li, Jing Shao, Yi Li, Junfu Wang, Yong Xue, Jinyue Zhang, Shuo Dong.  (2021)  Synthesis of SERS imprinted membrane based on Ag/ESM with different morphologies for selective detection of antibiotics in aqueous sample.  OPTICAL MATERIALS,  121  (111581). 
6. Yu Wang, Jin-Yi Yang, Ying He, Lu Li, Jian-Xin Huang, Yuan-Xin Tian, Hong Wang, Zhen-Lin Xu, Yu-Dong Shen.  (2021)  Development of Time-Resolved Fluorescence Immunochromatographic Assays for Simultaneously Detecting Tylosin and Tilmicosin in Milk in Group-Screening Manner.  Foods,  10  (8): (1838). 
7. Yicheng Dou, Tingting Yan, Zhipeng Zhang, Qiya Sun, Lin Wang, Yongmei Li.  (2021)  Heterogeneous activation of peroxydisulfate by sulfur-doped g-C3N4 under visible-light irradiation: Implications for the degradation of spiramycin and an assessment of N-nitrosodimethylamine formation potential.  JOURNAL OF HAZARDOUS MATERIALS,  406  (124328). 
8. Yumin Leng, Fang Hu, Chunhua Ma, Chenxi Du, Linfeng Ma, Jiao Xu, Qiyuan Lin, Zhipei Sang, Zhiwen Lu.  (2019)  Simple, rapid, sensitive, selective and label-free lincomycin detection by using HAuCl4 and NaOH.  RSC Advances,  (48): (28248-28252). 
9. Chan-Yuan YAO, Jin-Yi YANG, Zhen-Lin XU, Hong WANG, Hong-Tao LEI, Yuan-Ming SUN, Yuan-Xin TIAN, Yu-Dong SHEN.  (2018)  Indirect Competitive Enzyme-Linked Immunosorbent Assay for Detection of Tylosin in Milk and Water Samples.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,  46  (1275). 
10. Yajuan Li, Yanyang Wu, Kui Chen, Bin Wu, Lijun Ji, Jiawen Zhu.  (2018)  Partition behavior of spiramycin in an aqueous two-phase system based on polyethylene glycol and sulfates.  SEPARATION SCIENCE AND TECHNOLOGY,     
11. Li'na Qiao, Sihua Qian, Yuhui Wang, Shifeng Yan, Hengwei Lin.  (2018)  Carbon-Dots-Based Lab-On-a-Nanoparticle Approach for the Detection and Differentiation of Antibiotics.  CHEMISTRY-A EUROPEAN JOURNAL,  24  (18): (4703-4709). 
12. Xuejun Cui, Rongguo Li, Xiaofei Liu, Jingfeng Wang, Xueqi Leng, Xiaolei Song, Qianqian Pei, Yu Wang, Su Liu, Jiadong Huang.  (2018)  Low-background and visual detection of antibiotic based on target-activated colorimetric split peroxidase DNAzyme coupled with dual nicking enzyme signal amplification.  ANALYTICA CHIMICA ACTA,  997  (1). 
13. Xiaochuan Zhang, Lili Jin, Zhe Cui, Changhao Zhang, Xue Wu, Hyun Park, Hongmei Quan, Chunmei Jin.  (2016)  Antiparasitic effects of oxymatrine and matrine against Toxoplasma gondii in vitro and in vivo.  EXPERIMENTAL PARASITOLOGY,  165  (95). 
14. Xiansong Shi, Xingyuan Wang, Tianci Feng, Tong Ju, Jianghai Long, Congcong Yin, Zhe Zhang, Yong Wang.  (2024)  A Cationic Three-Dimensional Covalent Organic Framework Membrane for Nanofiltration of Molecules and Rare Earth Ions.  JOURNAL OF MEMBRANE SCIENCE,    (123240). 
15. Guowen Qin, Huilin Song, Dan Wu, Yuqi Zhang, Peiqi Li, Kaidi Zhang, Yang Zheng, Shunli Ji.  (2024)  Design of a novel green bio-based organic–inorganic hybrid material for cost-effective and sustainable monitoring of antibiotic residues.  GREEN CHEMISTRY,     
16. Jieqiong Wang, Weifeng Yan, Xu Cheng, Yonggang Tong, Sihong Wang, Chunmei Jin.  (2024)  The Intestinal Barrier Protective Effect of Indole Aldehyde Derivatives on Acute Toxoplasma gondii Infection.  MOLECULES,  29  (21): (5024). 

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.