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Sofituzumab vedotin (anti-MUC16) - Primary antibody, specific to MUC16, >90% (SDS-PAGE&SEC), high purity, Human IgG1, BINDING AGENT of Mucin-16 binding agent, BINDING AGENT of Mucin-16 binding agent

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: MC-VC-PAB-MMAE
In stock
Item Number
Ab183328
Grouped product items
SKU Size
Availability
Price Qty
Ab183328-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab183328-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$919.90
Ab183328-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90
Ab183328-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$3,679.90

Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)

Basic Description

Product Name Sofituzumab vedotin (anti-MUC16) - Primary antibody, specific to MUC16, >90% (SDS-PAGE&SEC), high purity, Human IgG1, BINDING AGENT of Mucin-16 binding agent
Synonyms CA 125 antibody | CA-125 antibody | CA125 antibody | CA125 ovarian cancer antigen antibody | Cancer antigen 125 antibody | FLJ14303 antibody | MUC 16 antibody | MUC-16 antibody | MUC16 antibody | MUC16_HUMAN antibody | Mucin 16 antibody | Mucin 16 cell su
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MUC16
Conjugation MC-VC-PAB-MMAE
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type BINDING AGENT
Mechanism of action BINDING AGENT of Mucin-16 binding agent
Product Description

Sofituzumab vedotin (anti-MUC16) is a MMAE-containing anti-MUC16 antibody-drug conjugate (ADC) with a protease-cleavable linker. Sofituzumab vedotin (anti-MUC16) can be used for the research of cancer.
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Purity >90% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1418200-58-4

Associated Targets(Human)

MUC16 Tbio Mucin-16 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Sofituzumab vedotin (anti-MUC16) (Ab183328) - Flow Cytometry
Flow Cytometry analysis of HeLa at 1×105 cell/well can bind Sofituzumab vedotin (anti-MUC16) (Ab183328) with the EC ₅₀  of 90.0 ng/mL.

Sofituzumab vedotin (anti-MUC16) (Ab183328) - SEC
The purity of Sofituzumab vedotin (anti-MUC16) (Ab183328) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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