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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab183328-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$189.90
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Ab183328-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$919.90
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Ab183328-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
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Ab183328-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$3,679.90
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Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
| Product Name | Sofituzumab vedotin (anti-MUC16) - Primary antibody, specific to MUC16, >90% (SDS-PAGE&SEC), high purity, Human IgG1, BINDING AGENT of Mucin-16 binding agent |
|---|---|
| Synonyms | CA 125 antibody | CA-125 antibody | CA125 antibody | CA125 ovarian cancer antigen antibody | Cancer antigen 125 antibody | FLJ14303 antibody | MUC 16 antibody | MUC-16 antibody | MUC16 antibody | MUC16_HUMAN antibody | Mucin 16 antibody | Mucin 16 cell su |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | MUC16 |
| Conjugation | MC-VC-PAB-MMAE |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | BINDING AGENT |
| Mechanism of action | BINDING AGENT of Mucin-16 binding agent |
| Product Description |
Sofituzumab vedotin (anti-MUC16) is a MMAE-containing anti-MUC16 antibody-drug conjugate (ADC) with a protease-cleavable linker. Sofituzumab vedotin (anti-MUC16) can be used for the research of cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Purity | >90% (SDS-PAGE&SEC) |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1418200-58-4 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Sofituzumab vedotin (anti-MUC16) (Ab183328) - Flow Cytometry
Flow Cytometry analysis of HeLa at 1×105 cell/well can bind Sofituzumab vedotin (anti-MUC16) (Ab183328) with the EC
₅₀
of 90.0 ng/mL.
Sofituzumab vedotin (anti-MUC16) (Ab183328) - SEC
The purity of Sofituzumab vedotin (anti-MUC16) (Ab183328) is more than 95% verified by HPLC.