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slotoxin, Channel blocker of K Ca1.1, CAS No.401470-29-9, Channel blocker of K Ca1.1

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Item Number
rp174990
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SKU Size
Availability
Price Qty
rp174990-500μg
500μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,334.90
rp174990-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,334.90

Basic Description

Product Name slotoxin, Channel blocker of K Ca1.1, CAS No.401470-29-9
Synonyms Potassium channel toxin α-KTx 1.11 | SloTx
Grade Moligand™
Specifications & Purity Moligand™
Action Type CHANNEL BLOCKER
Mechanism of action Channel blocker of K Ca1.1

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic Polymers
Class Polypeptides
Subclass Not available
Intermediate Tree Nodes Not available
Direct Parent Polypeptides
Alternative Parents Peptides  Tyrosine and derivatives  Arginine and derivatives  Phenylalanine and derivatives  Pentacarboxylic acids and derivatives  Glutamic acid and derivatives  Aspartic acid and derivatives  Isoleucine and derivatives  Methionine and derivatives  Valine and derivatives  N-acyl-L-alpha-amino acids  Proline and derivatives  Serine and derivatives  Alpha amino acid amides  Tryptamines and derivatives  Cysteine and derivatives  Alanine and derivatives  3-alkylindoles  Amphetamines and derivatives  Pyrrolidinecarboxamides  N-acylpyrrolidines  1-hydroxy-2-unsubstituted benzenoids  N-acyl amines  Substituted pyrroles  Tertiary carboxylic acid amides  Heteroaromatic compounds  Secondary alcohols  Amino acids  Guanidines  Secondary carboxylic acid amides  Dialkylthioethers  Carboxylic acids  Carboximidamides  Azacyclic compounds  Sulfenyl compounds  Alkylthiols  Hydrocarbon derivatives  Carbonyl compounds  Imines  Monoalkylamines  Organic oxides  Primary alcohols  
Molecular Framework Aromatic heteropolycyclic compounds
Substituents Polypeptide - Alpha peptide - Tyrosine or derivatives - Arginine or derivatives - Phenylalanine or derivatives - Pentacarboxylic acid or derivatives - Glutamic acid or derivatives - Methionine or derivatives - Aspartic acid or derivatives - Isoleucine or derivatives - N-acyl-alpha amino acid or derivatives - N-acyl-alpha-amino acid - N-acyl-l-alpha-amino acid - Valine or derivatives - Proline or derivatives - Cysteine or derivatives - Serine or derivatives - Alpha-amino acid amide - Triptan - Alanine or derivatives - Amphetamine or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - 3-alkylindole - Indole - Indole or derivatives - Pyrrolidine carboxylic acid or derivatives - Pyrrolidine-2-carboxamide - N-acylpyrrolidine - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Monocyclic benzene moiety - Fatty acyl - Substituted pyrrole - Fatty amide - N-acyl-amine - Benzenoid - Heteroaromatic compound - Tertiary carboxylic acid amide - Pyrrole - Pyrrolidine - Amino acid or derivatives - Amino acid - Carboxamide group - Guanidine - Secondary carboxylic acid amide - Secondary alcohol - Alkylthiol - Carboxylic acid derivative - Carboxylic acid - Azacycle - Organoheterocyclic compound - Dialkylthioether - Sulfenyl compound - Carboximidamide - Thioether - Alcohol - Amine - Organic oxide - Primary amine - Carbonyl group - Hydrocarbon derivative - Primary alcohol - Imine - Organosulfur compound - Organooxygen compound - Primary aliphatic amine - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors Not available

Associated Targets(Human)

KCNMA1 Tclin Calcium-activated potassium channel subunit alpha-1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Storage and Shipping

CAS 401470-29-9

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Genetic information

Alternate Names Potassium channel toxin α-KTx 1.11 | SloTx
Reference
  • 1. Kinetics and inhibition of recombinant human cystathionine gamma-lyase. Toward the rational control of transsulfuration., The Journal of biological chemistry, Steegborn, C C and 7 more authors.
  • 2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences., Proceedings of the National Academy of Sciences of the United States of America, Strausberg, Robert L RL and 83 more authors.
  • 3. Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH)., Human genetics, Wang, Jian J and Hegele, Robert A RA.
  • 4. Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase., Biochemical and biophysical research communications, Lu, Y Y, O'Dowd, B F BF, Orrego, H H and Israel, Y Y.
  • 5. Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration., Clinical genetics, Wang, J J, Huff, A M AM, Spence, J D JD and Hegele, R A RA.
  • 6. Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1., The Journal of biological chemistry, Yang, Guangdong G, Cao, Kun K, Wu, Lingyun L and Wang, Rui R.
  • 7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)., Genome research, Gerhard, Daniela S DS and 115 more authors.
  • 8. Towards a proteome-scale map of the human protein-protein interaction network., Nature, Rual, Jean-François JF and 37 more authors.
  • 9. The DNA sequence and biological annotation of human chromosome 1., Nature, Gregory, S G SG and 178 more authors.
  • 10. Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer., International journal of cancer, Moore, Lee E LE and 14 more authors. more

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