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SKI-178 - 10mM in DMSO, high purity , CAS No.1259484-97-3

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
S421090
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SKU Size
Availability
Price Qty
S421090-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$190.90

Basic Description

Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Information

SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines.

Names and Identifiers

IUPAC Name N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
INCHI InChI=1S/C21H22N4O4/c1-13(15-7-10-19(28-3)20(11-15)29-4)22-25-21(26)18-12-17(23-24-18)14-5-8-16(27-2)9-6-14/h5-12H,1-4H3,(H,23,24)(H,25,26)
InChIKey GMFUWEBOUKIKRP-UHFFFAOYSA-N
Smiles CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
Isomeric SMILES CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
PubChem CID 1356476
Molecular Weight 394.4

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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