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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
S413386-1mg
|
1mg |
2
|
$19.90
|
|
|
S413386-5mg
|
5mg |
2
|
$81.90
|
|
|
S413386-10mg
|
10mg |
2
|
$140.90
|
|
|
S413386-25mg
|
25mg |
2
|
$271.90
|
|
|
S413386-50mg
|
50mg |
2
|
$434.90
|
|
|
S413386-100mg
|
100mg |
2
|
$652.90
|
|
| Specifications & Purity | ≥98% |
|---|---|
| Biochemical and Physiological Mechanisms | SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines. |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Information SKI-178 is a potent inhibitor of sphingosine kinase-1 (SphK1) and SphK2. SKI-178 induces apoptosis in a CDK1-dependent manner in human acute myeloid leukemia cell lines. |
| Pubchem Sid | 504760468 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504760468 |
| IUPAC Name | N-[1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide |
| INCHI | InChI=1S/C21H22N4O4/c1-13(15-7-10-19(28-3)20(11-15)29-4)22-25-21(26)18-12-17(23-24-18)14-5-8-16(27-2)9-6-14/h5-12H,1-4H3,(H,23,24)(H,25,26) |
| InChIKey | GMFUWEBOUKIKRP-UHFFFAOYSA-N |
| Smiles | CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC |
| Isomeric SMILES | CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC |
| PubChem CID | 1356476 |
| Molecular Weight | 394.4 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 10, 2025 | S413386 | |
| Certificate of Analysis | Jun 10, 2025 | S413386 | |
| Certificate of Analysis | Jun 10, 2025 | S413386 | |
| Certificate of Analysis | Jun 10, 2025 | S413386 | |
| Certificate of Analysis | Jun 10, 2025 | S413386 | |
| Certificate of Analysis | Jun 10, 2025 | S413386 |