SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC 50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC 50 of 11.5 μM. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC 50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC 50 of 11.5 μM SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity .
In Vitro
SIRT1-IN-1 (compound 2) has little effect on SIRT3 (IC 50 >100 μM) and HDAC (IC 50 >100 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
This compound belongs to the class of organic compounds known as carbazoles. These are compounds containing a three ring system containing a pyrrole ring fused on either side to a benzene ring.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
