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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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S649190-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$378.90
|
|
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S649190-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$640.90
|
|
|
S649190-25mg
|
25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,357.90
|
|
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S649190-50mg
|
50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,314.90
|
|
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S649190-100mg
|
100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$4,005.90
|
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| Specifications & Purity | ≥99% |
|---|---|
| Biochemical and Physiological Mechanisms | (+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1. |
| Storage Temp | Store at 2-8°C |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1. In Vitro (+)-SHIN1 ((+)-RZ-2994) is potent against cytosolic SHMT1 with an IC 50 for blocking growth of less than 50 nM and 870 nM in SHMT2 deletion cells and HCT-116 cells, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |
| IUPAC Name | (4S)-6-amino-4-[3-(hydroxymethyl)-5-phenylphenyl]-3-methyl-4-propan-2-yl-2H-pyrano[2,3-c]pyrazole-5-carbonitrile |
|---|---|
| INCHI | InChI=1S/C24H24N4O2/c1-14(2)24(20(12-25)22(26)30-23-21(24)15(3)27-28-23)19-10-16(13-29)9-18(11-19)17-7-5-4-6-8-17/h4-11,14,29H,13,26H2,1-3H3,(H,27,28)/t24-/m0/s1 |
| InChIKey | VVVOFJZXKJKHTD-DEOSSOPVSA-N |
| Smiles | CC1=C2C(=NN1)OC(=C(C2(C3=CC(=CC(=C3)C4=CC=CC=C4)CO)C(C)C)C#N)N |
| PubChem CID | 134335071 |
| Molecular Weight | 400.47 |
| Solubility | DMSO : ≥ 100 mg/mL (249.71 mM) |
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