Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab182819-100μg
|
100μg |
10
|
$109.90
|
|
|
Ab182819-1mg
|
1mg |
4
|
$519.90
|
|
|
Ab182819-5mg
|
5mg |
1
|
$1,399.90
|
|
|
Ab182819-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,239.90
|
|
Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Setrusumab (anti-Sclerostin) - Primary antibody, specific to SOST, Human IgG2SA, INHIBITOR of Sclerostin inhibitor |
|---|---|
| Synonyms | BEER antibody | CDD antibody | Cortical hyperostosis with syndactyly antibody | Sclerosteosis antibody | Sclerostin antibody | Sost antibody | SOST_HUMAN antibody | SOST1 antibody | UNQ2976/PRO7455/PRO7476 antibody | VBCH antibody | SOST | sclerostin | VB |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | SOST |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Sclerostin inhibitor |
| Product Description |
Setrusumab (anti-Sclerostin) is a fully humanized monoclonal antibody targets sclerostin. Setrusumab (anti-Sclerostin) efftively improves bone strength. Setrusumab (anti-Sclerostin) can be used for the resesrch of Osteogenesis Imperfecta (OI) and cancer. |
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | lambdaC2 |
| SDS-PAGE | 143.44 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1847394-95-9 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Setrusumab (anti-Sclerostin) (Ab182819) - ELISA
Immobilized cyno-Sclerostin-ECD-his at 2.0 μg/mL can bind Setrusumab (anti-Sclerostin) (Ab182819) with the EC50 of 66.97 ng/mL.
Setrusumab (anti-Sclerostin) (Ab182819) - SEC
The purity of Setrusumab (anti-Sclerostin) (Ab182819) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jun 18, 2024 | Ab182819 | |
| Certificate of Analysis | Jun 18, 2024 | Ab182819 | |
| Certificate of Analysis | Jun 18, 2024 | Ab182819 |
Starting at $69.90