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SCR7 pyrazine - ≥98%(HPLC), high purity , CAS No.14892-97-8

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 14892-97-8
Molecular Weight: 332.38
MDL number: MFCD02167478
PubChem CID: 10688007
PubChem SID: 504765581

In stock

Item Number

S287286

Grouped product items
SKU	Size	Availability	Price
S287286-25mg	25mg	4	$358.90
S287286-50mg	50mg	2	$608.90
S287286-100mg	100mg	1	$1,096.90
S287286-250mg	250mg	1	$2,466.90
S287286-1g	1g	1	$8,879.90

Enhances HDR efficiency

View related series

Apoptosis (4276) Bioactive compounds (12) Cell Cycle (2830) Cell Cycle/DNA Damage (2602) CRISPR/Cas9 (10) DNA Damage (697) DNA/RNA Synthesis (362)

Basic Description

Synonyms	SCR7 pyrazine, >=98% (HPLC) \| HY-107845 \| Z3244609139 \| 6,7-diphenyl-2-thioxo-2,3-dihydropteridin-4(1H)-one \| AKOS025404699 \| SCR7 pyrazine \| 6,7-diphenyl-2-sulfanylpteridin-4-ol \| Oprea1_571617 \| 6,7-diphenyl-2-sulfanyl-3H-pteridin-4-one \| GM-0028 \| SCHE
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiencyin vitroup to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pteridines and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pteridines and derivatives
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Pteridines and derivatives
Alternative Parents	Pyrimidones Pyrimidinethiones 2-Thiopyrimidines Pyrazines Benzene and substituted derivatives Vinylogous amides Heteroaromatic compounds Thioureas Lactams Azacyclic compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Pteridine - 2-thiopyrimidine - Thiopyrimidine - Pyrimidone - Pyrimidinethione - Monocyclic benzene moiety - Pyrazine - Benzenoid - Pyrimidine - Heteroaromatic compound - Vinylogous amide - Lactam - Thiourea - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as pteridines and derivatives. These are polycyclic aromatic compounds containing a pteridine moiety, which consists of a pyrimidine fused to a pyrazine ring to form pyrimido(4,5-b)pyrazine.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504765581
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504765581
IUPAC Name	6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
INCHI	InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
InChIKey	GSRTWXVBHGOUBU-UHFFFAOYSA-N
Smiles	C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
Isomeric SMILES	C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
PubChem CID	10688007
Molecular Weight	332.38

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
F2306387	Certificate of Analysis	May 13, 2023	S287286
F2306382	Certificate of Analysis	May 13, 2023	S287286
F2306381	Certificate of Analysis	May 13, 2023	S287286
F2306386	Certificate of Analysis	May 13, 2023	S287286
F2306389	Certificate of Analysis	May 13, 2023	S287286
F2306385	Certificate of Analysis	May 13, 2023	S287286
F2306383	Certificate of Analysis	May 13, 2023	S287286
F2306384	Certificate of Analysis	May 13, 2023	S287286
F2306388	Certificate of Analysis	May 13, 2023	S287286

Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 33.44, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 6.69, Max Conc. mM: 20
Sensitivity	Heat Sensitive
Melt Point(°C)	209 °C
Molecular Weight	332.400 g/mol
XLogP3	2.900
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	332.073 Da
Monoisotopic Mass	332.073 Da
Topological Polar Surface Area	99.000 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	487.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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