SA 57 - 98%, high purity , CAS No.1346169-63-8, Inhibitor of αβ-Hydrolase 6;Inhibitor of Fatty acid amide hydrolase;Inhibitor of Monoacylglycerol lipase

Grade & Purity:

Moligand™

In stock

Item Number

S287063

Grouped product items
SKU	Size	Availability	Price
S287063-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$166.90
S287063-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$409.90
S287063-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$700.90
S287063-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,129.90
S287063-250mg	250mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$3,150.90

Potent FAAH inhibitor

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Synonyms	4-[2-(4-Chlorophenyl)ethyl]-1-piperidinecarboxylic acid 2-(methylamino)-2-oxoethyl ester \| (Z)-2-((4-(4-chlorophenethyl)piperidine-1-carbonyl)oxy)-N-methylacetimidic acid
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Potent inhibitor of fatty acid amide hydrolase (FAAH) (IC50<10 nM). Also inhibits MAGL at higher concentrations (IC50values are 410 nM and 1.4μM respectively). Inhibits both human and mouse FAAH enzymes. Exhibits inhibitory activity against FAAH, MAGL and
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Inhibitor of αβ-Hydrolase 6;Inhibitor of Fatty acid amide hydrolase;Inhibitor of Monoacylglycerol lipase

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Piperidines
Subclass	Piperidinecarboxylic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Piperidinecarboxylic acids
Alternative Parents	Chlorobenzenes Aryl chlorides Carbamate esters Secondary carboxylic acid amides Azacyclic compounds Organonitrogen compounds Organochlorides Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Piperidinecarboxylic acid - Chlorobenzene - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Carbamic acid ester - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organonitrogen compound - Organochloride - Organohalogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organic oxygen compound - Organooxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as piperidinecarboxylic acids. These are compounds containing a piperidine ring which bears a carboxylic acid group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

IUPAC Name	[2-(methylamino)-2-oxoethyl] 4-[2-(4-chlorophenyl)ethyl]piperidine-1-carboxylate
INCHI	InChI=1S/C17H23ClN2O3/c1-19-16(21)12-23-17(22)20-10-8-14(9-11-20)3-2-13-4-6-15(18)7-5-13/h4-7,14H,2-3,8-12H2,1H3,(H,19,21)
InChIKey	JFSSVCSHPDLFCM-UHFFFAOYSA-N
Smiles	CNC(=O)COC(=O)N1CCC(CC1)CCC2=CC=C(C=C2)Cl
Isomeric SMILES	CNC(=O)COC(=O)N1CCC(CC1)CCC2=CC=C(C=C2)Cl
PubChem CID	44589122
Molecular Weight	338.83

Solubility	Solvent:DMSO, Max Conc. mg/mL: 8.47, Max Conc. mM: 25; Solvent:ethanol, Max Conc. mg/mL: 6.78, Max Conc. mM: 20
Molecular Weight	338.800 g/mol
XLogP3	3.300
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	6
Exact Mass	338.14 Da
Monoisotopic Mass	338.14 Da
Topological Polar Surface Area	58.600 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	389.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Basic Description