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Rosmanol - 10mM in DMSO, high purity , CAS No.80225-53-2(DMSO)

COA

Grade & Purity:

10mM in DMSO

Cas Number: 80225-53-2(DMSO)
Molecular Weight: 346.42

In stock

Item Number

R655950

Grouped product items
SKU	Size	Availability	Price	Qty
R655950-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$198.90

Phenols Polyphenols

View related series

Compound libraries (12325) COX (258) Immunology/Inflammation (1929) Phenols Polyphenols (41)

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect.
Storage Temp	Store at -80°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Rosmanol could inhibit the oxidation of low density lipoprotein (LPL) and significantly inhibit lipopolysaccharide induced iNOS and COX-2 expression, with anti-inflammatory effect. In Vitro Rosmanol exhibits the strongest inhibition on cell viability with IC 50 approximately 42 μM. Rosmanol might suppress cancer cell proliferation or induce cancer cell undergoing apoptosis that lead to cell growth-inhibition. With 50 μM of Rosmanol treatment, the percentage of COLO 205 cells undergoing apoptosis increase dramatically from 9 h (29%) to 24 h (51%). Within 24 h of treatment with 50 μM Rosmanol, COLO 205 cells exhibit significant morphological changes and chromosomal condensation, which is indicative of apoptotic cell death. Carnosol is a lipid protector against attack by O 2. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Names and Identifiers

Smiles	CC(C)C1=C(C(=C2C(=C1)C(C3C4C2(CCCC4(C)C)C(=O)O3)O)O)O
Molecular Weight	346.42

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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